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NCT00926783 · ClinicalTrials.gov registry record · Phase 4

Selective Complex Fractionated Atrial Electrograms (CFAE) Targeting for Atrial Fibrillation

A Phase 4 study of Atrial Fibrillation, sponsored by Biosense Webster.

Completed
Registry status
Phase 4
Development phase
86
Enrollment target
7
Study locations

NCT00926783: Completed Phase 4 study of Atrial Fibrillation, sponsored by Biosense Webster.

NCT00926783 is a Phase 4 study of Atrial Fibrillation that has completed, run by Biosense Webster. The registered enrollment target is 86 participants, below the 2,996-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (97% lower). The trial reports 7 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00926783, a Phase 4 study of Atrial Fibrillation, has completed, sponsored by Biosense Webster.

COMPLETED
Registry status
Phase 4
Development phase
86 participants
Enrollment target
7
Study locations

Study Summary

This study will be a multicenter, open, prospective, randomized trial. Patients with either paroxysmal or persistent atrial fibrillation will be considered for the study. (For US, only paroxysmal atrial fibrillation will be considered.) Eligible subjects will be randomized into one of two arms in the study: (1) targeted CFAE ablation or (2) generalized CFAE ablation. Both techniques will then be followed by PVAI (pulmonary vein antral isolation) as part of a hybrid ablation strategy. The nature of the ablation procedures does not allow physicians to be blinded to the randomization.

Primary Outcome

Proportion of subjects who were free from atrial arrhythmia (no recurrence of atrial fibrillation, atrial flutter, and atrial tachycardia (AF/AFL/AT)) between Day 91 and Day 365 post first ablation procedure.

Conditions Studied

Interventions

  • PROCEDURE CFAE ablation

Study Locations (7)

Ontario

  • Hamilton Health Sciences Centre - Hamilton
  • Southlake Regional Health Center - Newmarket

Quebec

  • Montreal Heart Institute - Montreal
  • Hopital Laval - Institut universitaire de cardiologie et de pneumonologie - Québec

Illinois

  • Loyola University Medical Center - Maywood

Maryland

  • Johns Hopkins University - Baltimore

South Australia

  • Royal Adelaide Hospital - Adelaide

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2009-08
Est. Completion 2013-09
Phase Phase 4
Biosense Webster

18 total trials

What the finished NCT00926783 record still lists

NCT00926783 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, below the 2,996-participant average among 202 other Atrial Fibrillation trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Atrial Fibrillation appearing as the primary indexed condition, and to 1 intervention - of which CFAE ablation is the first listed.

NCT00926783 lists 7 locations in 5 states (Ontario, Quebec, Illinois).

Frequently Asked Questions

What is clinical trial NCT00926783 about?

NCT00926783 is a clinical study titled "Selective Complex Fractionated Atrial Electrograms (CFAE) Targeting for Atrial Fibrillation". This study will be a multicenter, open, prospective, randomized trial. Patients with either paroxysmal or persistent atrial fibrillation will be considered for the study. (For US, only paroxysmal atrial fibrillation will be considered.) Eligible subjects will be randomized into one of two arms in th...

What is the current status of trial NCT00926783?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 86 participants. The study started on 2009-08. Estimated completion is 2013-09.

What conditions does trial NCT00926783 study?

This clinical trial studies the following conditions: Atrial Fibrillation.

What interventions are being tested in trial NCT00926783?

The interventions under investigation include: CFAE ablation (PROCEDURE).

Who is sponsoring clinical trial NCT00926783?

This trial is sponsored by Biosense Webster, which has 18 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00926783 being conducted?

This trial has 7 study locations across Illinois, Maryland, South Australia, Ontario, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Atrial Fibrillation

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00926783's enrollment target sits among peer trials

86 148th of 202 higher than 55 of 202 other Atrial Fibrillation trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Atrial Fibrillation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00926783, the US trial registry maintained by the National Library of Medicine. NCT00926783 (small enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.