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Improving the Selection of Patients With Glioblastoma Multiforme for Treatment With Epidermal Growth Factor Receptor Inhibitor Therapies
NCT00897663 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This laboratory study is looking at tissue samples from patients with glioblastoma multiforme to identify biomarkers that may improve the selection of patients for epidermal growth factor receptor inhibitor therapies.
Conditions Studied
Interventions
- GENETIC gene expression analysis
- GENETIC microarray analysis
- GENETIC protein expression analysis
- OTHER immunohistochemistry staining method
- OTHER diagnostic laboratory biomarker analysis
Study Locations (10)
Iowa
- Siouxland Hematology-Oncology Associates, LLP — Sioux City
- Mercy Medical Center - Sioux City — Sioux City
- St. Luke's Regional Medical Center — Sioux City
North Dakota
- Medcenter One Hospital Cancer Care Center — Bismarck
- Mid Dakota Clinic, PC — Bismarck
- St. Alexius Medical Center Cancer Center — Bismarck
Arizona
- Mayo Clinic Scottsdale — Scottsdale
Florida
- Mayo Clinic - Jacksonville — Jacksonville
Minnesota
- Mayo Clinic Cancer Center — Rochester
South Dakota
- Rapid City Regional Hospital — Rapid City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2006-11 |
| Est. Completion | 2018-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00897663
The ClinicalTrials.gov registry entry for NCT00897663 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alliance for Clinical Trials in Oncology, which has 147 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 5 interventions — of which gene expression analysis is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00897663 reports 10 study locations spanning 6 distinct geographic areas — top geographies include Iowa, North Dakota, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00897663 about?
NCT00897663 is a clinical study titled "Improving the Selection of Patients With Glioblastoma Multiforme for Treatment With Epidermal Growth Factor Receptor Inhibitor Therapies". RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This laboratory study is looking at tissue samples from pa...
What is the current status of trial NCT00897663?
This trial is currently completed. The enrollment target is 56 participants. The study started on 2006-11. Estimated completion is 2018-01.
What conditions does trial NCT00897663 study?
This clinical trial studies the following conditions: Brain and Central Nervous System Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00897663?
The interventions under investigation include: gene expression analysis (GENETIC), microarray analysis (GENETIC), protein expression analysis (GENETIC), immunohistochemistry staining method (OTHER), diagnostic laboratory biomarker analysis (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00897663?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 147 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00897663 being conducted?
This trial has 10 study locations across Arizona, Florida, Iowa, Minnesota, North Dakota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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