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NCT00875615 · ClinicalTrials.gov registry record · Phase 2
Cisplatin or Carboplatin and Sorafenib in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery
A Phase 2 study of Liver Cancer, sponsored by University of Miami.
- Completed
- Registry status
- Phase 2
- Development phase
- 11
- Enrollment target
- 1
- Study location
NCT00875615: Completed Phase 2 study of Liver Cancer, sponsored by University of Miami.
NCT00875615 is a Phase 2 study of Liver Cancer that has completed, run by University of Miami. The registered enrollment target is 11 participants, below the 448-participant average among 78 other Liver Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00875615, a Phase 2 study of Liver Cancer, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 11 participants
- Enrollment target
- 1
- Study location
Study Summary
RATIONALE: Drugs used in chemotherapy, such as cisplatin and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Infusing chemotherapy directly into the liver and giving it together with sorafenib may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects of infusing cisplatin or carboplatin directly into the liver and giving it together with sorafenib in treating patients with liver cancer that cannot be removed by surgery.
Primary Outcome
The number of subjects experiencing adverse events after receiving protocol therapy.
Conditions Studied
Interventions
- DRUG Carboplatin
- DRUG Cisplatin
- DRUG Sorafenib
Study Locations (1)
Florida
- University of Miami Sylvester Comprehensive Cancer Center - Miami - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2008-12 |
| Est. Completion | 2012-06 |
| Phase | Phase 2 |
What the finished NCT00875615 record still lists
NCT00875615 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 448-participant average among 78 other Liver Cancer trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Liver Cancer appearing as the primary indexed condition, and to 3 interventions - of which Carboplatin is the first listed.
NCT00875615 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT00875615 about?
NCT00875615 is a clinical study titled "Cisplatin or Carboplatin and Sorafenib in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery". RATIONALE: Drugs used in chemotherapy, such as cisplatin and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and b...
What is the current status of trial NCT00875615?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2008-12. Estimated completion is 2012-06.
What conditions does trial NCT00875615 study?
This clinical trial studies the following conditions: Liver Cancer.
What interventions are being tested in trial NCT00875615?
The interventions under investigation include: Carboplatin (DRUG), Cisplatin (DRUG), Sorafenib (DRUG).
Who is sponsoring clinical trial NCT00875615?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00875615 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Liver Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00875615's enrollment target sits among peer trials
11 74th of 78 higher than 5 of 78 other Liver Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Liver Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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