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NCT00840749 · ClinicalTrials.gov registry record · NA
Randomized Study to Compare CyberKnife to Surgical Resection In Stage I Non-small Cell Lung Cancer
A NA study, sponsored by Accuray Incorporated.
- Terminated
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT00840749: Clinical Trial NA study, sponsored by Accuray Incorporated.
NCT00840749 is a NA study that was terminated before completion, run by Accuray Incorporated. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00840749, a NA study, was terminated before completion, sponsored by Accuray Incorporated.
- TERMINATED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
Lung cancer remains the most frequent cause of cancer death in both men and women in the world. Surgical resection using lobectomy with mediastinal lymph node dissection or sampling has been a standard of care for operable early stage NSCLC. Several studies have reported high local control and survival using SBRT in stage I NSCLC patients. SBRT is now an accepted treatment for medically inoperable patients with stage I NSCLC and patients with operable stage I lung cancer are entered on clinical protocols. The purpose of this study is to conduct a phase III randomized study to compare CyberKnife SBRT with surgery, the current standard of care for stage I operable NSCLC.
Primary Outcome
The study power was calculated for sample size of 420 patients, enrolled over 7 years. The actual enrollment was 36 patients over 4 years. The study was therefore terminated due to lack of enrollment. The sample size does not allow to analysis of the primary outcome. While the study data is not mature enough to evaluate the endpoints of the study, we will attempt to describe the results gleaned from the existing patient population.
Interventions
- PROCEDURE Surgery
- RADIATION CyberKnife Stereotactic Radiotherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2008-12 |
| Est. Completion | 2013-03 |
| Phase | NA |
Why NCT00840749 stopped before completion
NCT00840749 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Surgery is the first listed.
NCT00840749 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00840749 about?
NCT00840749 is a clinical study titled "Randomized Study to Compare CyberKnife to Surgical Resection In Stage I Non-small Cell Lung Cancer". Lung cancer remains the most frequent cause of cancer death in both men and women in the world. Surgical resection using lobectomy with mediastinal lymph node dissection or sampling has been a standard of care for operable early stage NSCLC. Several studies have reported high local control and survi...
What is the current status of trial NCT00840749?
This trial is currently terminated. It is a NA study. The enrollment target is 36 participants. The study started on 2008-12. Estimated completion is 2013-03.
What interventions are being tested in trial NCT00840749?
The interventions under investigation include: Surgery (PROCEDURE), CyberKnife Stereotactic Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT00840749?
This trial is sponsored by Accuray Incorporated, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00840749's enrollment target sits among peer trials
36 1541st of 2000 higher than 437 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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