Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00821977 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Long-Term Safety of Vildagliptin as Monotherapy in Patients With Type 2 Diabetes

A Phase 2 study of Diabetes Mellitus, Type 2, sponsored by Novartis.

Completed
Registry status
Phase 2
Development phase
338
Enrollment target
20
Study locations

NCT00821977: Completed Phase 2 study of Diabetes Mellitus, Type 2, sponsored by Novartis.

NCT00821977 is a Phase 2 study of Diabetes Mellitus, Type 2 that has completed, run by Novartis. The registered enrollment target is 338 participants, below the 4,484-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (92% lower). The trial reports 20 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00821977, a Phase 2 study of Diabetes Mellitus, Type 2, has completed, sponsored by Novartis.

COMPLETED
Registry status
Phase 2
Development phase
338 participants
Enrollment target
20
Study locations

Study Summary

This is a 2-3 period parallel group study with an adaptive element in Type 2 diabetes patients receiving vildagliptin as monotherapy.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Vildagliptin

Study Locations (20)

California

  • Sall Research Medical Center - Artesia
  • Associated Pharmaceutical Research - Buena Park
  • Providence Research - Burbank
  • Burbank - Lovelace Scientific Resources, Inc. - Burbank
  • Lucita M. Cruz, M.D., Inc. - Norwalk
  • California Research Foundation - San Diego
  • Ritchken and First MDs - San Diego
  • San Diego Sports Medicine Research and Family Care - San Diego
  • Crest Clinical Trials - Santa Ana

Arizona

  • Horizon Clinical Research Associates, PLLC - Gilbert
  • Vista Medical Research, Inc - Mesa
  • Clinical Research Advantage - Mesa
  • Hope Clinical Research - Phoenix
  • Anasazi Internal Medicine - Phoenix
  • Tatum Ridge Internal Medicine - Phoenix
  • Paradigm Clinical - Tucson
  • Tucson Clinical Research - Tucson

Arkansas

  • Medical Investigations, Inc. - Little Rock
  • Paul W. Davis, MD - Pine Bluff

Alabama

  • Advanced Clinical Research - Pell City

Trial Details

FieldValue
Enrollment Target 338 participants
Start Date 2008-11
Est. Completion 2010-10
Phase Phase 2
Novartis

265 total trials

What the finished NCT00821977 record still lists

NCT00821977 is an interventional study that assigns participants to a tested intervention. The registered 338 participants enrollment target is mid-sized for trials with a published cap, below the 4,484-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (92% lower).

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00821977 names 20 study sites across 4 states, led by California, Arizona, Arkansas.

Frequently Asked Questions

What is clinical trial NCT00821977 about?

NCT00821977 is a clinical study titled "Efficacy and Long-Term Safety of Vildagliptin as Monotherapy in Patients With Type 2 Diabetes". This is a 2-3 period parallel group study with an adaptive element in Type 2 diabetes patients receiving vildagliptin as monotherapy.

What is the current status of trial NCT00821977?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 338 participants. The study started on 2008-11. Estimated completion is 2010-10.

What conditions does trial NCT00821977 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.

What interventions are being tested in trial NCT00821977?

The interventions under investigation include: Placebo (DRUG), Vildagliptin (DRUG).

Who is sponsoring clinical trial NCT00821977?

This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00821977 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes Mellitus, Type 2

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00821977's enrollment target sits among peer trials

338 107th of 348 higher than 242 of 348 other Diabetes Mellitus, Type 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03253263 · 338 participants · Phase 2

    A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

  • NCT05658731 · 338 participants · NA

    Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

  • NCT06022939 · 338 participants · Phase 3

    Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

  • NCT04176172 · 340 participants · Phase 3

    Optimizing Tobacco Use Treatment for PLWHA

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00821977, the US trial registry maintained by the National Library of Medicine. NCT00821977 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.