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NCT00796562 · ClinicalTrials.gov registry record · Phase 2

Safety Study of Bone Marrow Transplant Using Mismatched Tissue Followed by Chemotherapy

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 2
Development phase
107
Enrollment target

NCT00796562: Completed Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

NCT00796562 is a Phase 2 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 107 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00796562, a Phase 2 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 2
Development phase
107 participants
Enrollment target

Study Summary

The purpose of this study is to see if giving high dose chemotherapy and total body irradiation before and repeating high dose chemotherapy after a bone marrow transplant could reduce the incidence of graft rejection and disease for patients with blood cancers

Primary Outcome

Percentage of participants who achieved donor chimerism \>=95%.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Busulfan
  • RADIATION Total body irradiation

Trial Details

FieldValue
Enrollment Target 107 participants
Start Date 2008-12
Est. Completion 2016-11
Phase Phase 2

What the finished NCT00796562 record still lists

NCT00796562 is an interventional study that assigns participants to a tested intervention. The registered 107 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% lower).

The record links to 0 conditions, and to 3 interventions - of which Cyclophosphamide is the first listed.

NCT00796562 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00796562 about?

NCT00796562 is a clinical study titled "Safety Study of Bone Marrow Transplant Using Mismatched Tissue Followed by Chemotherapy". The purpose of this study is to see if giving high dose chemotherapy and total body irradiation before and repeating high dose chemotherapy after a bone marrow transplant could reduce the incidence of graft rejection and disease for patients with blood cancers

What is the current status of trial NCT00796562?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 107 participants. The study started on 2008-12. Estimated completion is 2016-11.

What interventions are being tested in trial NCT00796562?

The interventions under investigation include: Cyclophosphamide (DRUG), Busulfan (DRUG), Total body irradiation (RADIATION).

Who is sponsoring clinical trial NCT00796562?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00796562's enrollment target sits among peer trials

107 646th of 2000 higher than 1,353 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00796562, the US trial registry maintained by the National Library of Medicine. NCT00796562 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.