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NCT00795860 · ClinicalTrials.gov registry record · NA
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT00795860 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 36 participants.
The verdict
NCT00795860, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
Clearly the effects of diet and exercise are beneficial for obese persons, but the underlying mechanisms for the improvements in metabolic health are not completely clear. Although mounting evidence suggests that alterations in lipid metabolism in persons with abdominal obesity are associated with a several medical complications, including diabetes, little is known about the factors responsible for this effect. The project in this application is designed to examine how the addition of endurance exercise training to a weight-loss program alters whole-body fatty acid availability, uptake, and oxidation as well as the expression of cellular factors that regulate these processes. In addition, we will evaluate whether these alterations are associated with improvements in insulin sensitivity. In the end, these experiments will provide insight into the cellular and whole-body adaptations in fatty acid metabolism in response to weight-loss and exercise training that may lead to enhancement of insulin sensitivity. Identifying relationships between gene expression, whole-body fatty acid metabolism and clinical outcome measurements, such as insulin sensitivity, may lead to improvements in the therapeutic and/or the preventative approach to obesity and its co-morbidities.
Interventions
- BEHAVIORAL Weight loss - diet only
- BEHAVIORAL Weight loss plus exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2003-06 |
| Est. Completion | 2007-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00795860
The ClinicalTrials.gov registry entry for NCT00795860 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Weight loss - diet only is the first listed.
NCT00795860 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00795860 about?
NCT00795860 is a clinical study titled "Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise". Clearly the effects of diet and exercise are beneficial for obese persons, but the underlying mechanisms for the improvements in metabolic health are not completely clear. Although mounting evidence suggests that alterations in lipid metabolism in persons with abdominal obesity are associated with a...
What is the current status of trial NCT00795860?
This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2003-06. Estimated completion is 2007-01.
What interventions are being tested in trial NCT00795860?
The interventions under investigation include: Weight loss - diet only (BEHAVIORAL), Weight loss plus exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT00795860?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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