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COMPLETED Phase 2

Prevention Study in Adult Patients Suffering From Migraine Headaches

NCT00742209 · View on ClinicalTrials.gov ↗

Study Summary

Purpose of the study is to evaluate dose response relationship, efficacy, safety and tolerability of target doses of GSK1838262 compared to placebo in the prophylactic treatment of migraine headache. Once subjects complete the baseline and meet the randomization criteria, they will complete a 5-wk flexible titration period and then enter the 12 week maintenance period.

Interventions

  • DRUG Placebo
  • DRUG GSK1838262

Study Locations (20)

California

  • GSK Investigational Site — Anaheim
  • GSK Investigational Site — Newport Beach
  • GSK Investigational Site — Redlands
  • GSK Investigational Site — San Francisco
  • GSK Investigational Site — Santa Monica
  • GSK Investigational Site — Westlake Village

Colorado

  • GSK Investigational Site — Colorado Springs
  • GSK Investigational Site — Colorado Springs
  • GSK Investigational Site — Denver

Florida

  • GSK Investigational Site — DeLand
  • GSK Investigational Site — Sunrise
  • GSK Investigational Site — West Palm Beach

Arizona

  • GSK Investigational Site — Phoenix
  • GSK Investigational Site — Phoenix

Georgia

  • GSK Investigational Site — Atlanta
  • GSK Investigational Site — Stockbridge

Alabama

  • GSK Investigational Site — Birmingham

Illinois

  • GSK Investigational Site — Chicago

Kansas

  • GSK Investigational Site — Wichita

Trial Details

FieldValue
Enrollment Target 526 participants
Start Date 2008-08
Est. Completion 2010-06
Phase Phase 2

Sponsor

XenoPort

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00742209

The ClinicalTrials.gov registry entry for NCT00742209 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 526 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is XenoPort, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Migraine appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00742209 reports 20 study locations spanning 9 distinct geographic areas — top geographies include California, Colorado, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00742209 about?

NCT00742209 is a clinical study titled "Prevention Study in Adult Patients Suffering From Migraine Headaches". Purpose of the study is to evaluate dose response relationship, efficacy, safety and tolerability of target doses of GSK1838262 compared to placebo in the prophylactic treatment of migraine headache. Once subjects complete the baseline and meet the randomization criteria, they will complete a 5-wk f...

What is the current status of trial NCT00742209?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 526 participants. The study started on 2008-08. Estimated completion is 2010-06.

What conditions does trial NCT00742209 study?

This clinical trial studies the following conditions: Migraine, Migraine Disorders. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00742209?

The interventions under investigation include: Placebo (DRUG), GSK1838262 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00742209?

This trial is sponsored by XenoPort, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00742209 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial