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NCT06728553 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy Trial of MTX101 2mg for the Acute Treatment of Migraine in Adults
A Phase 2 study of Migraine, sponsored by Manistee Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 78
- Enrollment target
- 7
- Study locations
NCT06728553 is a Phase 2 study of Migraine that has completed, run by Manistee Therapeutics. The registered enrollment target is 78 participants, below the 357-participant average among 102 other Migraine trials with a reported enrollment target (78% lower). The trial reports 7 study locations across 5 states.
The verdict
NCT06728553, a Phase 2 study of Migraine, has completed, sponsored by Manistee Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 78 participants
- Enrollment target
- 7
- Study locations
Study Summary
The goal of this clinical trial is to learn if drug MTX101 works to treat acute migraine attacks in adults. It will also learn about the safety of the drug MTX101. The main questions it aims to answer are: Does the drug MTX101 lower headache pain for participants and the need to use a rescue medication? What side effects, if any, do participants have when taking the drug MTX101? Researchers will compare the drug MTX101 to a placebo (a look-alike substance that contains no drug) to see if the drug MTX101 works to treat acute migraine attacks. Participants will: Take the drug MTX101 or a placebo to treat 1 migraine attack with each treatment. Visit the clinic twice and have one phone call over a 4 week period for checkups and tests. Keep a diary of their symptoms and the number of times they use a rescue medication.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG MTX101
Study Locations (7)
California
- Kaizen Brain Center - La Jolla
- Clinical Research Institute, LLC - Santa Monica
Florida
- Brainstorm Research - Miami
- Synergy Clinical Research/Emerald Coast Center for Neurological Disorders - Pensacola
Louisiana
- DelRicht Research - New Orleans
Michigan
- QUEST Research Institute - Farmington Hills
Utah
- Wasatch Clinical Research - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 78 participants |
| Start Date | 2025-02-24 |
| Est. Completion | 2025-07-28 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06728553
The ClinicalTrials.gov registry entry for NCT06728553 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 78 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 357-participant average among 102 other Migraine trials with a reported enrollment target (78% lower). The listed sponsor is Manistee Therapeutics, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Migraine appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06728553 reports 7 study locations spanning 5 distinct geographic areas - top geographies include California, Florida, Louisiana.
Frequently Asked Questions
What is clinical trial NCT06728553 about?
NCT06728553 is a clinical study titled "Safety and Efficacy Trial of MTX101 2mg for the Acute Treatment of Migraine in Adults". The goal of this clinical trial is to learn if drug MTX101 works to treat acute migraine attacks in adults. It will also learn about the safety of the drug MTX101. The main questions it aims to answer are: Does the drug MTX101 lower headache pain for participants and the need to use a rescue medica...
What is the current status of trial NCT06728553?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 78 participants. The study started on 2025-02-24. Estimated completion is 2025-07-28.
What conditions does trial NCT06728553 study?
This clinical trial studies the following conditions: Migraine.
What interventions are being tested in trial NCT06728553?
The interventions under investigation include: Placebo (DRUG), MTX101 (DRUG).
Who is sponsoring clinical trial NCT06728553?
This trial is sponsored by Manistee Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06728553 being conducted?
This trial has 7 study locations across California, Florida, Louisiana, Michigan, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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