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NCT04930887 · ClinicalTrials.gov registry record · Phase 2
Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain
A Phase 2 study of Migraine and Cluster Headache, sponsored by Stanford University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT04930887: Recruiting Phase 2 study of Migraine and Cluster Headache, sponsored by Stanford University.
NCT04930887 is a Phase 2 study of Migraine and Cluster Headache that is actively recruiting participants, run by Stanford University. The registered enrollment target is 15 participants, below the 358-participant average among 102 other Migraine trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04930887, a Phase 2 study of Migraine and Cluster Headache, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel (Bupivacaine) for the treatment of craniofacial pain. This study would be conducted in a prospective, randomized, double-blinded, placebo- controlled, and cross-over fashion. We aim to investigate whether the administration of Exparel (Bupivacaine) to the lateral nasal wall may positively impact craniofacial pain and functional outcomes, in patients who experience relief with the topical application of Lidocaine (routinely given prior to almost all ENT endoscopy).
Primary Outcome
Scores range from 0-10 (0=no pain, 10=worst pain)
Conditions Studied
Interventions
- DRUG Saline
- DRUG Exparel (Bupivacaine Liposome)
Study Locations (1)
California
- Peter H Hwang - Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2023-02-01 |
| Est. Completion | 2030-06 |
| Phase | Phase 2 |
What NCT04930887 shows while recruiting
NCT04930887 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 358-participant average among 102 other Migraine trials with a reported enrollment target (96% lower).
The record links to 6 conditions, with Migraine appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT04930887 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04930887 about?
NCT04930887 is a clinical study titled "Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain". Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel (Bupivacaine) for the treatment of craniofacial pain. This study would be conducte...
What is the current status of trial NCT04930887?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2023-02-01. Estimated completion is 2030-06.
What conditions does trial NCT04930887 study?
This clinical trial studies the following conditions: Migraine, Cluster Headache, Paroxysmal Hemicrania, Craniofacial Pain, Trigeminal Autonomic Cephalgia.
What interventions are being tested in trial NCT04930887?
The interventions under investigation include: Saline (DRUG), Exparel (Bupivacaine Liposome) (DRUG).
Who is sponsoring clinical trial NCT04930887?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04930887 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Migraine
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04930887's enrollment target sits among peer trials
15 100th of 102 higher than 3 of 102 other Migraine trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Migraine trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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CHOCOlate MeLatonin for AdolescenT MigrainE
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