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NCT00727402 · ClinicalTrials.gov registry record
Longitudinal Evaluation of Silicone Hydrogel (LASH) Study
A clinical trial, sponsored by National Eye Institute (NEI).
- Completed
- Registry status
- 205
- Enrollment target
NCT00727402: Completed study, sponsored by National Eye Institute (NEI).
NCT00727402 is a clinical trial that has completed, run by National Eye Institute (NEI). The registered enrollment target is 205 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00727402 has completed, sponsored by National Eye Institute (NEI).
- COMPLETED
- Registry status
- 205 participants
- Enrollment target
Study Summary
The LASH Contact Lens Study is a prospective longitudinal study of silicone hydrogel (SH) contact lens wearers who sleep in their lenses for up to 29 consecutive nights (30 days) of continuous wear (CW), with monthly disposal. Up to 207 healthy nearsighted or farsighted patients with minimal or no astigmatism and no contraindications to CW lens use will be followed for 1 year. The primary outcome measure is the time to development of a corneal inflammatory event (CIE) as defined by slit lamp findings and patient symptoms. The main exposure of interest is corneal staining. Other key exploratory variables include bacterial contamination of study lenses and inflammatory mediators found in the tear film.
Primary Outcome
Unadjusted cumulative incidence of corneal inflammatory events (CIE)using survival analysis methods. CIE are corneal infiltrates found in an otherwise clear cornea.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 205 participants |
| Start Date | 2006-10 |
| Est. Completion | 2009-10 |
What the finished NCT00727402 record still lists
NCT00727402 is an observational study that tracks outcomes without assigning an intervention. The registered 205 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00727402 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00727402 about?
NCT00727402 is a clinical study titled "Longitudinal Evaluation of Silicone Hydrogel (LASH) Study". The LASH Contact Lens Study is a prospective longitudinal study of silicone hydrogel (SH) contact lens wearers who sleep in their lenses for up to 29 consecutive nights (30 days) of continuous wear (CW), with monthly disposal. Up to 207 healthy nearsighted or farsighted patients with minimal or no a...
What is the current status of trial NCT00727402?
This trial is currently completed. The enrollment target is 205 participants. The study started on 2006-10. Estimated completion is 2009-10.
Who is sponsoring clinical trial NCT00727402?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
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