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NCT00720876 · ClinicalTrials.gov registry record · Phase 2

Vorinostat and Rituximab in Treating Patients With Indolent Non-Hodgkin Lymphoma

A Phase 2 study of Lymphoma, sponsored by City of Hope Medical Center.

Completed
Registry status
Phase 2
Development phase
30
Enrollment target
3
Study locations

NCT00720876 is a Phase 2 study of Lymphoma that has completed, run by City of Hope Medical Center. The registered enrollment target is 30 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 1 state.

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The verdict

NCT00720876, a Phase 2 study of Lymphoma, has completed, sponsored by City of Hope Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
30 participants
Enrollment target
3
Study locations

Study Summary

RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Giving vorinostat together with rituximab may kill more cancer cells. PURPOSE: This phase II trial is studying the side effects of giving vorinostat together with rituximab and to see how well it works in treating patients with indolent non-Hodgkin lymphoma.

Conditions Studied

Interventions

  • DRUG vorinostat
  • BIOLOGICAL rituximab

Study Locations (3)

California

  • Tower Cancer Research Foundation - Beverly Hills
  • City of Hope Comprehensive Cancer Center - Duarte
  • City of Hope Medical Group - Pasadena

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2008-07-23
Est. Completion 2017-06-08
Phase Phase 2

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT00720876

The ClinicalTrials.gov registry entry for NCT00720876 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (94% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which vorinostat is the first listed.

NCT00720876 reports 3 study locations spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00720876 about?

NCT00720876 is a clinical study titled "Vorinostat and Rituximab in Treating Patients With Indolent Non-Hodgkin Lymphoma". RATIONALE: Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill the...

What is the current status of trial NCT00720876?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2008-07-23. Estimated completion is 2017-06-08.

What conditions does trial NCT00720876 study?

This clinical trial studies the following conditions: Lymphoma.

What interventions are being tested in trial NCT00720876?

The interventions under investigation include: vorinostat (DRUG), rituximab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00720876?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00720876 being conducted?

This trial has 3 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.