Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00704288 · ClinicalTrials.gov registry record · Phase 2

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

A Phase 2 study, sponsored by Exelixis.

Completed
Registry status
Phase 2
Development phase
222
Enrollment target

NCT00704288 is a Phase 2 study that has completed, run by Exelixis. The registered enrollment target is 222 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00704288, a Phase 2 study, has completed, sponsored by Exelixis.

COMPLETED
Registry status
Phase 2
Development phase
222 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the objective response rate and 6-month progression-free survival rate of XL184 in subjects with recurrent or progressive glioblastoma multiforme. XL184 is a new chemical entity that inhibits VEGFR2, MET and RET, kinases implicated in tumor formation, growth and migration.

Interventions

  • DRUG XL184

Trial Details

FieldValue
Enrollment Target 222 participants
Start Date 2008-05
Est. Completion 2012-12
Phase Phase 2

Sponsor

Exelixis

48 total trials

What the Registry Record Tells You About NCT00704288

The ClinicalTrials.gov registry entry for NCT00704288 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 222 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Exelixis, which has 48 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which XL184 is the first listed.

NCT00704288 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00704288 about?

NCT00704288 is a clinical study titled "Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme". The purpose of this study is to evaluate the objective response rate and 6-month progression-free survival rate of XL184 in subjects with recurrent or progressive glioblastoma multiforme. XL184 is a new chemical entity that inhibits VEGFR2, MET and RET, kinases implicated in tumor formation, growth ...

What is the current status of trial NCT00704288?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 222 participants. The study started on 2008-05. Estimated completion is 2012-12.

What interventions are being tested in trial NCT00704288?

The interventions under investigation include: XL184 (DRUG).

Who is sponsoring clinical trial NCT00704288?

This trial is sponsored by Exelixis, which has 48 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.