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NCT00697268 · ClinicalTrials.gov registry record

p11 Protein Levels in Patients With Major Depressive Disorder Treated With Citalopram

A clinical trial of Depression, sponsored by National Institute of Mental Health (NIMH).

Completed
Registry status
38
Enrollment target
1
Study location

NCT00697268 is a study of Depression that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 38 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00697268, a study of Depression, has completed, sponsored by National Institute of Mental Health (NIMH).

COMPLETED
Registry status
38 participants
Enrollment target
1
Study location

Study Summary

This study will compare levels of p11 protein in people with and without major depressive disorder (MDD) and examine if p11 levels in patients are affected by treatment with citalopram (Celexa). Healthy normal volunteers and patients with chronic or recurrent major depression between 18 and 65 years of age may be eligible for this study. Participants undergo the following tests and procedures: Healthy Volunteers * Psychiatric interview and medical examination, questions about family history * Blood draw Patients with MDD Phase 1 - Evaluation and Discontinuation of Medications * Physical examination, electrocardiogram, blood tests * Gradual antidepressant medication withdrawal, followed by 2- to 6-week drug-free period. If needed, medicines for anxiety and difficulty sleeping may be prescribed. Phase 2 Citalopram Treatment * Start daily citalopram treatment * Evaluations at the start of phase 2 and every week for 8 weeks with following procedures: * Symptoms ratings interview and questionnaires * Review of side effects and new medications * Blood pressure and pulse measurements * Blood and urine tests At the end of the study, plans are developed for long-term treatment and transfer of care to the patient s own physician. ...

Conditions Studied

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2008-06-03
Est. Completion 2016-07-28

What the Registry Record Tells You About NCT00697268

The ClinicalTrials.gov registry entry for NCT00697268 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower). The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 0 interventions.

NCT00697268 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00697268 about?

NCT00697268 is a clinical study titled "p11 Protein Levels in Patients With Major Depressive Disorder Treated With Citalopram". This study will compare levels of p11 protein in people with and without major depressive disorder (MDD) and examine if p11 levels in patients are affected by treatment with citalopram (Celexa). Healthy normal volunteers and patients with chronic or recurrent major depression between 18 and 65 year...

What is the current status of trial NCT00697268?

This trial is currently completed. The enrollment target is 38 participants. The study started on 2008-06-03. Estimated completion is 2016-07-28.

What conditions does trial NCT00697268 study?

This clinical trial studies the following conditions: Depression.

Who is sponsoring clinical trial NCT00697268?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00697268 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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