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NCT00678717 · ClinicalTrials.gov registry record · NA

Microneurography and Spinal Cord Stimulation in Chronic Visceral Pain

A NA study, sponsored by Vanderbilt University Medical Center.

Terminated
Registry status
NA
Development phase
36
Enrollment target

NCT00678717: Clinical Trial NA study, sponsored by Vanderbilt University Medical Center.

NCT00678717 is a NA study that was terminated before completion, run by Vanderbilt University Medical Center. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00678717, a NA study, was terminated before completion, sponsored by Vanderbilt University Medical Center.

TERMINATED
Registry status
NA
Development phase
36 participants
Enrollment target

Study Summary

The purpose of this study is to assess the effect of the spinal cord stimulator (A small wire is surgically implanted under the skin. Low-level electrical signals are then transmitted through the lead to the spinal cord to alleviate pain. Using a magnetic remote control, the patients can turn the current on and off, or adjust the intensity.) on the autonomic nervous system (sympathetic and parasympathetic). Some studies support that the spinal cord stimulation suppresses or decreases sympathetic outflow (the sympathetic nervous system is the one that provide us with the "flight and fight response" and the parasympathetic nervous system is the one that works while we "sleep, rest and digest".). The sympathetic nervous system is important in blood pressure regulation also. However, there are not reports regarding the effect of the spinal cord stimulation on blood pressure regulation in chronic visceral pain patients. Most clinical trials are focus on the effect of the spinal cord stimulation on pain relief. We think we could use blood pressure, heart rate and special analysis of these signals and their relationship to other pain measurements to assess the effect of the spinal cord stimulation in an objective way.

Primary Outcome

Microneurography directly assesses muscle sympathetic nerve activity (MSNA)

Interventions

  • PROCEDURE Autonomic Evaluation

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2008-02
Est. Completion 2009-01-23
Phase NA

Why NCT00678717 stopped before completion

NCT00678717 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which Autonomic Evaluation is the first listed.

NCT00678717 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00678717 about?

NCT00678717 is a clinical study titled "Microneurography and Spinal Cord Stimulation in Chronic Visceral Pain". The purpose of this study is to assess the effect of the spinal cord stimulator (A small wire is surgically implanted under the skin. Low-level electrical signals are then transmitted through the lead to the spinal cord to alleviate pain. Using a magnetic remote control, the patients can turn the cu...

What is the current status of trial NCT00678717?

This trial is currently terminated. It is a NA study. The enrollment target is 36 participants. The study started on 2008-02. Estimated completion is 2009-01-23.

What interventions are being tested in trial NCT00678717?

The interventions under investigation include: Autonomic Evaluation (PROCEDURE).

Who is sponsoring clinical trial NCT00678717?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00678717's enrollment target sits among peer trials

36 1541st of 2000 higher than 437 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00678717, the US trial registry maintained by the National Library of Medicine. NCT00678717 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.