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NCT00631072 · ClinicalTrials.gov registry record · Phase 1

In Vitro Expanded Autologous Invariant Natural Killer Cells in Cancer

A Phase 1 study of Malignant Melanoma, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
Phase 1
Development phase
9
Enrollment target
2
Study locations

NCT00631072 is a Phase 1 study of Malignant Melanoma that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 9 participants, below the 183-participant average among 28 other Malignant Melanoma trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT00631072, a Phase 1 study of Malignant Melanoma, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
Phase 1
Development phase
9 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this research study is to determine whether we can purify and grow a population of cells from the participants blood (iNKT cells) and then safely give them back to the participant in increased numbers, and whether these cells will then stimulate the bodies own immune response against the cancer. These iNKT cells have been used in laboratory studies and information from these and other research studies suggest that increasing the number of these cells in the blood can stimulate the immune response against tumors.

Conditions Studied

Interventions

  • DRUG GM-CSF
  • BIOLOGICAL INKT

Study Locations (2)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston
  • Dana-Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2008-02
Est. Completion 2015-04
Phase Phase 1

What the Registry Record Tells You About NCT00631072

The ClinicalTrials.gov registry entry for NCT00631072 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 183-participant average among 28 other Malignant Melanoma trials with a reported enrollment target (95% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Malignant Melanoma appearing as the primary indexed condition, and to 2 interventions - of which GM-CSF is the first listed.

NCT00631072 reports 2 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00631072 about?

NCT00631072 is a clinical study titled "In Vitro Expanded Autologous Invariant Natural Killer Cells in Cancer". The purpose of this research study is to determine whether we can purify and grow a population of cells from the participants blood (iNKT cells) and then safely give them back to the participant in increased numbers, and whether these cells will then stimulate the bodies own immune response against ...

What is the current status of trial NCT00631072?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2008-02. Estimated completion is 2015-04.

What conditions does trial NCT00631072 study?

This clinical trial studies the following conditions: Malignant Melanoma.

What interventions are being tested in trial NCT00631072?

The interventions under investigation include: GM-CSF (DRUG), INKT (BIOLOGICAL).

Who is sponsoring clinical trial NCT00631072?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00631072 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.