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NCT00610987 · ClinicalTrials.gov registry record · NA
Antibiotic Prophylaxis in Orthopaedic Traumatology
A NA study of Wounds and Injuries and Fractures, Closed, sponsored by University of Missouri-Columbia.
- Completed
- Registry status
- NA
- Development phase
- 178
- Enrollment target
- 1
- Study location
NCT00610987: Completed NA study of Wounds and Injuries and Fractures, Closed, sponsored by University of Missouri-Columbia.
NCT00610987 is a NA study of Wounds and Injuries and Fractures, Closed that has completed, run by University of Missouri-Columbia. The registered enrollment target is 178 participants, below the 497-participant average among 27 other Wounds and Injuries trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00610987, a NA study of Wounds and Injuries and Fractures, Closed, has completed, sponsored by University of Missouri-Columbia.
- COMPLETED
- Registry status
- NA
- Development phase
- 178 participants
- Enrollment target
- 1
- Study location
Study Summary
It has been established that providing antibiotic prophylaxis after closed fracture fixation with implants or prosthetic devices has beneficial effects. However, the optimal duration of antibiotic prophylaxis after orthopaedic trauma surgery is not well-defined. Most studies comparing single-dose prophylaxis with multiple-dose prophylaxis have not shown beneficial effects of additional doses. Our proposed study is intended to further define the appropriate duration of antibiotic (cefazolin) administration for surgical prophylaxis in the treatment of closed fractures. We will randomly assigned patients into two groups, hopefully differentiated only by the duration of antibiotic administration (single dose vs. 24 hours). We will follow these patients until fracture healing and determine if there is a difference in the incidence of infection.
Primary Outcome
The primary endpoint was infection.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG cefazolin
Study Locations (1)
Missouri
- University of Missouri - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 178 participants |
| Start Date | 2008-01 |
| Est. Completion | 2014-01 |
| Phase | NA |
What the finished NCT00610987 record still lists
NCT00610987 is an interventional study that assigns participants to a tested intervention. The registered 178 participants enrollment target is mid-sized for trials with a published cap, below the 497-participant average among 27 other Wounds and Injuries trials with a reported enrollment target (64% lower).
The record links to 2 conditions, with Wounds and Injuries appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00610987 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT00610987 about?
NCT00610987 is a clinical study titled "Antibiotic Prophylaxis in Orthopaedic Traumatology". It has been established that providing antibiotic prophylaxis after closed fracture fixation with implants or prosthetic devices has beneficial effects. However, the optimal duration of antibiotic prophylaxis after orthopaedic trauma surgery is not well-defined. Most studies comparing single-dose pr...
What is the current status of trial NCT00610987?
This trial is currently completed. It is a NA study. The enrollment target is 178 participants. The study started on 2008-01. Estimated completion is 2014-01.
What conditions does trial NCT00610987 study?
This clinical trial studies the following conditions: Wounds and Injuries, Fractures, Closed.
What interventions are being tested in trial NCT00610987?
The interventions under investigation include: Placebo (DRUG), cefazolin (DRUG).
Who is sponsoring clinical trial NCT00610987?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00610987 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00610987's enrollment target sits among peer trials
178 15th of 27 higher than 13 of 27 other Wounds and Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Wounds and Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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