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NCT00586703 · ClinicalTrials.gov registry record · Phase 1
Safety Trial of NK Cell DLI 3-5/6 Family Member Following Nonmyeloablative ASCT
A Phase 1 study, sponsored by David Rizzieri, MD.
- Completed
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
NCT00586703: Completed Phase 1 study, sponsored by David Rizzieri, MD.
NCT00586703 is a Phase 1 study that has completed, run by David Rizzieri, MD. The registered enrollment target is 21 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00586703, a Phase 1 study, has completed, sponsored by David Rizzieri, MD.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
Study Summary
Evaluate the safety of natural killer (NK) cell infusion using CD56 monoclonal antibody selected with Miltenyi Biotec system following nonmyeloablative stem cell transplantation (SCT) from mismatched donors. This pilot study will evaluate toxicity including mortality, occurrence of acute graft versus host disease (aGVHD) and other severe toxicity.
Primary Outcome
Evaluate the safety of NK cell infusion using CD56 monoclonal antibody following nonmyeloablative stem cell transplantation from mismatched donors: Toxicity including mortality, occurrence of acute graft versus host disease (aGVHD) and other severe toxicity.
Interventions
- DEVICE NK-CD56
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2005-04 |
| Est. Completion | 2013-11 |
| Phase | Phase 1 |
What the finished NCT00586703 record still lists
NCT00586703 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower).
The record links to 0 conditions, and to 1 intervention - of which NK-CD56 is the first listed.
NCT00586703 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00586703 about?
NCT00586703 is a clinical study titled "Safety Trial of NK Cell DLI 3-5/6 Family Member Following Nonmyeloablative ASCT". Evaluate the safety of natural killer (NK) cell infusion using CD56 monoclonal antibody selected with Miltenyi Biotec system following nonmyeloablative stem cell transplantation (SCT) from mismatched donors. This pilot study will evaluate toxicity including mortality, occurrence of acute graft versu...
What is the current status of trial NCT00586703?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2005-04. Estimated completion is 2013-11.
What interventions are being tested in trial NCT00586703?
The interventions under investigation include: NK-CD56 (DEVICE).
Who is sponsoring clinical trial NCT00586703?
This trial is sponsored by David Rizzieri, MD, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00586703's enrollment target sits among peer trials
21 1615th of 2000 higher than 372 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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