Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00581568 · ClinicalTrials.gov registry record · Phase 1
Cutaneous Effects of Cryogen Spray Cooling
A Phase 1 study of Pain, sponsored by University of California, Irvine.
- Completed
- Registry status
- Phase 1
- Development phase
- 53
- Enrollment target
- 1
- Study location
NCT00581568: Completed Phase 1 study of Pain, sponsored by University of California, Irvine.
NCT00581568 is a Phase 1 study of Pain that has completed, run by University of California, Irvine. The registered enrollment target is 53 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00581568, a Phase 1 study of Pain, has completed, sponsored by University of California, Irvine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 53 participants
- Enrollment target
- 1
- Study location
Study Summary
Cryogen Spray Cooling spurt is applied to the skin surface immediately before laser exposure. As liquid cryogen rapidly evaporates, the superficial skin temperature is reduced as a result of supplying the latent heat of vaporization. Tetrafluoroethane, an environmentally compatible, non-toxic, non-flammable freon substitute, has been demonstrated in multiple studies to be a safe and effective cooling agent and is the only cryogenic compound currently approved for dermatologic use by the Food and Drug Administration.
Primary Outcome
Cryogen Spray Cooling spray cooling skin during laser treatment
Conditions Studied
Interventions
- OTHER Cutaneous Effects of Cryogen Spray Cooling
Study Locations (1)
California
- Beckman Laser Institute Medical and Surgical clinic - Irvine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2004-01 |
| Est. Completion | 2010-09 |
| Phase | Phase 1 |
What the finished NCT00581568 record still lists
NCT00581568 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 53 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 1 intervention - of which Cutaneous Effects of Cryogen Spray Cooling is the first listed.
NCT00581568 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00581568 about?
NCT00581568 is a clinical study titled "Cutaneous Effects of Cryogen Spray Cooling". Cryogen Spray Cooling spurt is applied to the skin surface immediately before laser exposure. As liquid cryogen rapidly evaporates, the superficial skin temperature is reduced as a result of supplying the latent heat of vaporization. Tetrafluoroethane, an environmentally compatible, non-toxic, non-f...
What is the current status of trial NCT00581568?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 53 participants. The study started on 2004-01. Estimated completion is 2010-09.
What conditions does trial NCT00581568 study?
This clinical trial studies the following conditions: Pain.
What interventions are being tested in trial NCT00581568?
The interventions under investigation include: Cutaneous Effects of Cryogen Spray Cooling (OTHER).
Who is sponsoring clinical trial NCT00581568?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00581568 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00581568's enrollment target sits among peer trials
53 252nd of 374 higher than 122 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy
RECRUITING · Phase 1
-
Evaluation of the Excretion of Suzetrigine Into Breast Milk in Healthy Lactating Female Participants
RECRUITING · Phase 1
-
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
RECRUITING · Phase 1
-
High Potency Cannabis: Acute and Protracted Effects
RECRUITING · Phase 1
-
Phase 1 Study of SBS-147 in Healthy Adults
RECRUITING · Phase 1
-
Patient Controlled Administration of Liquid Acetaminophen
RECRUITING · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04177004 · 53 participants · Phase 1
Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant
- NCT04199741 · 53 participants · Phase 1
PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56
- NCT04835129 · 53 participants · Phase 2
Isatuximab, Pomalidomide, Elotuzumab and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma
- NCT04913805 · 53 participants · Phase 2
Matching Perfusion and Metabolic Activity in HFpEF
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia