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NCT00554515 · ClinicalTrials.gov registry record · Phase 2

The High-Dose Aldesleukin (IL-2) "Select" Trial for Patients With Metastatic Renal Cell Carcinoma

A Phase 2 study of Metastatic Renal Cell Carcinoma, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
Phase 2
Development phase
123
Enrollment target
1
Study location

NCT00554515 is a Phase 2 study of Metastatic Renal Cell Carcinoma that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 123 participants, below the 140-participant average among 37 other Metastatic Renal Cell Carcinoma trials with a reported enrollment target (12% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00554515, a Phase 2 study of Metastatic Renal Cell Carcinoma, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
123 participants
Enrollment target
1
Study location

Study Summary

High-dose interleukin 2 (Proleukin, Novartis) (IL-2) is approved by the U.S Food and Drug Administration (FDA) for the treatment of metastatic kidney cancer and is a standard treatment of this disease. At the present time, IL-2 is the only therapy for kidney cancer that can produce a remission of disease that lasts after treatment is completed. However, most patients who receive IL-2 do not benefit and all patients experience potentially dangerous side effects. Recent research has suggested that certain patients may respond better to IL-2 than others. The Cytokine Working Group is currently conducting a clinical trial that aims to identify and confirm this research and narrow the application of IL-2 to those patients most likely to benefit.

Interventions

  • DRUG HD IL2

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 123 participants
Start Date 2006-11
Est. Completion 2013-10-31
Phase Phase 2

What the Registry Record Tells You About NCT00554515

The ClinicalTrials.gov registry entry for NCT00554515 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 123 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 140-participant average among 37 other Metastatic Renal Cell Carcinoma trials with a reported enrollment target (12% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Metastatic Renal Cell Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which HD IL2 is the first listed.

NCT00554515 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00554515 about?

NCT00554515 is a clinical study titled "The High-Dose Aldesleukin (IL-2) "Select" Trial for Patients With Metastatic Renal Cell Carcinoma". High-dose interleukin 2 (Proleukin, Novartis) (IL-2) is approved by the U.S Food and Drug Administration (FDA) for the treatment of metastatic kidney cancer and is a standard treatment of this disease. At the present time, IL-2 is the only therapy for kidney cancer that can produce a remission of di...

What is the current status of trial NCT00554515?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 123 participants. The study started on 2006-11. Estimated completion is 2013-10-31.

What conditions does trial NCT00554515 study?

This clinical trial studies the following conditions: Metastatic Renal Cell Carcinoma.

What interventions are being tested in trial NCT00554515?

The interventions under investigation include: HD IL2 (DRUG).

Who is sponsoring clinical trial NCT00554515?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00554515 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.