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NCT00527865 · ClinicalTrials.gov registry record · Phase 1

Single Dose Escalating Study of DAS181 in Adults

A Phase 1 study, sponsored by Ansun Biopharma.

Completed
Registry status
Phase 1
Development phase
36
Enrollment target

NCT00527865: Completed Phase 1 study, sponsored by Ansun Biopharma.

NCT00527865 is a Phase 1 study that has completed, run by Ansun Biopharma. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00527865, a Phase 1 study, has completed, sponsored by Ansun Biopharma.

COMPLETED
Registry status
Phase 1
Development phase
36 participants
Enrollment target

Study Summary

This study will evaluate the safety, tolerability, and systemic exposure of an experimental influenza (flu) treatment medication called DAS181. DAS181 is a dry powder that is administered via oral inhalation using a special device. Study participants will include up to 60 healthy, non-smoking males and females, ages 18-65. They will be given either DAS181 or placebo. Participants will remain in the clinic overnight to be watched for health changes for 24 hours after receiving the medication. Study procedures include: physical exams, chest x-rays, ECGs, lung function tests, collection of blood and urine samples, and throat swabs. Follow-up visits will occur on study days 2, 7, 14 +/- 1 day, and 30 +/- 2 days. Participants will be involved in the study for up to 61 days, which includes the screening period.

Interventions

  • DRUG Placebo
  • DRUG DAS181

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2007-10
Est. Completion 2009-01
Phase Phase 1
Ansun Biopharma

8 total trials

What the finished NCT00527865 record still lists

NCT00527865 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00527865 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00527865 about?

NCT00527865 is a clinical study titled "Single Dose Escalating Study of DAS181 in Adults". This study will evaluate the safety, tolerability, and systemic exposure of an experimental influenza (flu) treatment medication called DAS181. DAS181 is a dry powder that is administered via oral inhalation using a special device. Study participants will include up to 60 healthy, non-smoking males ...

What is the current status of trial NCT00527865?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2007-10. Estimated completion is 2009-01.

What interventions are being tested in trial NCT00527865?

The interventions under investigation include: Placebo (DRUG), DAS181 (DRUG).

Who is sponsoring clinical trial NCT00527865?

This trial is sponsored by Ansun Biopharma, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00527865's enrollment target sits among peer trials

36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00527865, the US trial registry maintained by the National Library of Medicine. NCT00527865 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.