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NCT00499694 · ClinicalTrials.gov registry record · NA

Satraplatin and Bevacizumab in Treating Patients With Metastatic Prostate Cancer Previously Treated With Docetaxel

A NA study, sponsored by Barbara Ann Karmanos Cancer Institute.

Completed
Registry status
NA
Development phase
31
Enrollment target

NCT00499694: Completed NA study, sponsored by Barbara Ann Karmanos Cancer Institute.

NCT00499694 is a NA study that has completed, run by Barbara Ann Karmanos Cancer Institute. The registered enrollment target is 31 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00499694, a NA study, has completed, sponsored by Barbara Ann Karmanos Cancer Institute.

COMPLETED
Registry status
NA
Development phase
31 participants
Enrollment target

Study Summary

RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Drugs used in chemotherapy, such as satraplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving satraplatin together with bevacizumab may kill more tumor cells. PURPOSE: This clinical trial is studying how well giving satraplatin together with bevacizumab works in treating patients with metastatic prostate cancer previously treated with docetaxel.

Primary Outcome

Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0), as a 20% increase in the sum of the longest diameter of target lesions, or a measurable increase in a non-target lesion, or the appearance of new lesions. TTP is measured using Kaplan-Meier product-limit.

Interventions

  • BIOLOGICAL bevacizumab
  • DRUG satraplatin

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2007-10
Est. Completion 2012-11
Phase NA

What the finished NCT00499694 record still lists

NCT00499694 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 2 interventions - of which bevacizumab is the first listed.

NCT00499694 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00499694 about?

NCT00499694 is a clinical study titled "Satraplatin and Bevacizumab in Treating Patients With Metastatic Prostate Cancer Previously Treated With Docetaxel". RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by bloc...

What is the current status of trial NCT00499694?

This trial is currently completed. It is a NA study. The enrollment target is 31 participants. The study started on 2007-10. Estimated completion is 2012-11.

What interventions are being tested in trial NCT00499694?

The interventions under investigation include: bevacizumab (BIOLOGICAL), satraplatin (DRUG).

Who is sponsoring clinical trial NCT00499694?

This trial is sponsored by Barbara Ann Karmanos Cancer Institute, which has 139 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00499694's enrollment target sits among peer trials

31 1592nd of 2000 higher than 408 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00499694, the US trial registry maintained by the National Library of Medicine. NCT00499694 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.