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NCT00490282 · ClinicalTrials.gov registry record · NA
A Pilot Trial of Image-Guided Adaptive Radiotherapy for Head and Neck Cancer
A NA study of Head and Neck Cancer and Oropharyngeal Cancer, sponsored by M.D. Anderson Cancer Center.
- Completed
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT00490282: Completed NA study of Head and Neck Cancer and Oropharyngeal Cancer, sponsored by M.D. Anderson Cancer Center.
NCT00490282 is a NA study of Head and Neck Cancer and Oropharyngeal Cancer that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 25 participants, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00490282, a NA study of Head and Neck Cancer and Oropharyngeal Cancer, has completed, sponsored by M.D. Anderson Cancer Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical research study is to use computed tomography (CT) scans to measure and guide your radiation therapy. Researchers want to learn if the CT scans can be used to adapt radiation therapy to the changes in normal tissue and to the shrinking of the tumor that may occur as a reaction to radiation therapy. Researchers also want to see if magnetic resonance imaging (MRI) scanning can detect certain changes in the tumor any earlier than with standard tests.
Primary Outcome
Comparison of mean dose in the Contralateral Parotid Gland and Ipsilateral Parotid Gland change between one adaptive replan (ART1) and two adaptive replans (ART2) planning relative to standard intensity-modulated radiation therapy (IMRT) planning. Dosimetric comparisons was performed using paired t-testing between plans, with patients serving as their own controls. The median trigger point for ART1 was the 16th treatment fraction. For ART2 patients, the median trigger points for the first and se
Conditions Studied
Interventions
- RADIATION Intensity Modulated Radiation Therapy
- RADIATION Adaptive Radiotherapy
Study Locations (1)
Texas
- University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2007-06 |
| Est. Completion | 2015-05 |
| Phase | NA |
What the finished NCT00490282 record still lists
NCT00490282 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (90% lower).
The record links to 2 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 2 interventions - of which Intensity Modulated Radiation Therapy is the first listed.
NCT00490282 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00490282 about?
NCT00490282 is a clinical study titled "A Pilot Trial of Image-Guided Adaptive Radiotherapy for Head and Neck Cancer". The goal of this clinical research study is to use computed tomography (CT) scans to measure and guide your radiation therapy. Researchers want to learn if the CT scans can be used to adapt radiation therapy to the changes in normal tissue and to the shrinking of the tumor that may occur as a reacti...
What is the current status of trial NCT00490282?
This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2007-06. Estimated completion is 2015-05.
What conditions does trial NCT00490282 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Oropharyngeal Cancer.
What interventions are being tested in trial NCT00490282?
The interventions under investigation include: Intensity Modulated Radiation Therapy (RADIATION), Adaptive Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT00490282?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00490282 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00490282's enrollment target sits among peer trials
25 196th of 250 higher than 47 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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