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NCT00487695 · ClinicalTrials.gov registry record · Phase 3

Confocal Endomicroscopy for Barrett's Esophagus

A Phase 3 study of Esophageal Adenocarcinoma and Barrett's Esophagus, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 3
Development phase
46
Enrollment target
1
Study location

NCT00487695: Completed Phase 3 study of Esophageal Adenocarcinoma and Barrett's Esophagus, sponsored by Johns Hopkins University.

NCT00487695 is a Phase 3 study of Esophageal Adenocarcinoma and Barrett's Esophagus that has completed, run by Johns Hopkins University. The registered enrollment target is 46 participants, below the 307-participant average among 43 other Esophageal Adenocarcinoma trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00487695, a Phase 3 study of Esophageal Adenocarcinoma and Barrett's Esophagus, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 3
Development phase
46 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine if confocal laser endomicroscopy (CLE) can improve detection of Barrett's esophagus, dysplasia, and early esophageal cancer.

Primary Outcome

The yield for neoplasia is calculated by the number of biopsies showing neoplasia over the total number of biopsies taken (normal + neoplastic biopsies)

Conditions Studied

Esophageal Adenocarcinoma Barrett's Esophagus

Interventions

  • DEVICE confocal laser endomicroscopy (CLE)
  • DEVICE standard endoscopy (EGD)

Study Locations (1)

Maryland

  • Johns Hopkins Hospital - Baltimore

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2007-04
Est. Completion 2008-09
Phase Phase 3
Johns Hopkins University

1,448 total trials

What the finished NCT00487695 record still lists

NCT00487695 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 307-participant average among 43 other Esophageal Adenocarcinoma trials with a reported enrollment target (85% lower).

The record links to 2 conditions, with Esophageal Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which confocal laser endomicroscopy (CLE) is the first listed.

NCT00487695 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT00487695 about?

NCT00487695 is a clinical study titled "Confocal Endomicroscopy for Barrett's Esophagus". The purpose of this study is to determine if confocal laser endomicroscopy (CLE) can improve detection of Barrett's esophagus, dysplasia, and early esophageal cancer.

What is the current status of trial NCT00487695?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 46 participants. The study started on 2007-04. Estimated completion is 2008-09.

What conditions does trial NCT00487695 study?

This clinical trial studies the following conditions: Esophageal Adenocarcinoma, Barrett's Esophagus.

What interventions are being tested in trial NCT00487695?

The interventions under investigation include: confocal laser endomicroscopy (CLE) (DEVICE), standard endoscopy (EGD) (DEVICE).

Who is sponsoring clinical trial NCT00487695?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00487695 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Esophageal Adenocarcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00487695's enrollment target sits among peer trials

46 29th of 43 higher than 15 of 43 other Esophageal Adenocarcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Esophageal Adenocarcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT00487695, the US trial registry maintained by the National Library of Medicine. NCT00487695 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.