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NCT00482690 · ClinicalTrials.gov registry record · NA

Analysis of Aldehyde Biomarkers of Exposure and Host Response

A NA study, sponsored by University of Nebraska.

Terminated
Registry status
NA
Development phase
35
Enrollment target

NCT00482690: Clinical Trial NA study, sponsored by University of Nebraska.

NCT00482690 is a NA study that was terminated before completion, run by University of Nebraska. The registered enrollment target is 35 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00482690, a NA study, was terminated before completion, sponsored by University of Nebraska.

TERMINATED
Registry status
NA
Development phase
35 participants
Enrollment target

Study Summary

Analysis of aldeyde biomarkers of exposure and host response The purpose of this prospective, open-label, clinical trial is to establish the feasibility and validity of exhaled breath condensate (EBC) biomarkers for use in studies designed to evaluate harm reduction strategies of smoking. This will be accomplished by measuring selected markers in EBC believed related to the pathogenesis of lung disease before and after a smoking cessation intervention.

Primary Outcome

Aledhydes were assessed in exhaled breath condensate by mass spec and chemical assay.

Interventions

  • DRUG nicotine polacrilex
  • DRUG nicotine transdermal system
  • DRUG nicotine inhaler

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2005-08-23
Est. Completion 2007-09-09
Phase NA
University of Nebraska

407 total trials

Why NCT00482690 stopped before completion

NCT00482690 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 3 interventions - of which nicotine polacrilex is the first listed.

NCT00482690 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00482690 about?

NCT00482690 is a clinical study titled "Analysis of Aldehyde Biomarkers of Exposure and Host Response". Analysis of aldeyde biomarkers of exposure and host response The purpose of this prospective, open-label, clinical trial is to establish the feasibility and validity of exhaled breath condensate (EBC) biomarkers for use in studies designed to evaluate harm reduction strategies of smoking. This will ...

What is the current status of trial NCT00482690?

This trial is currently terminated. It is a NA study. The enrollment target is 35 participants. The study started on 2005-08-23. Estimated completion is 2007-09-09.

What interventions are being tested in trial NCT00482690?

The interventions under investigation include: nicotine polacrilex (DRUG), nicotine transdermal system (DRUG), nicotine inhaler (DRUG).

Who is sponsoring clinical trial NCT00482690?

This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00482690's enrollment target sits among peer trials

35 1564th of 2000 higher than 431 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00482690, the US trial registry maintained by the National Library of Medicine. NCT00482690 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.