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NCT00457964 · ClinicalTrials.gov registry record · Phase 1
RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM
A Phase 1 study, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT00457964: Completed Phase 1 study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT00457964 is a Phase 1 study that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00457964, a Phase 1 study, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
The purpose of this research study is to find out what effects RAD001 has on angiomyolipomas of a person with Tuberous Sclerosis Complex and to determine the safe dose of RAD001 without toxicity. The hypothesis is that the drug will inhibit the growth of the angiomyolipomas and possibly even cause regression.
Interventions
- DRUG RAD001
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2005-08 |
| Est. Completion | 2013-07 |
| Phase | Phase 1 |
What the finished NCT00457964 record still lists
NCT00457964 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 1 intervention - of which RAD001 is the first listed.
NCT00457964 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00457964 about?
NCT00457964 is a clinical study titled "RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM". The purpose of this research study is to find out what effects RAD001 has on angiomyolipomas of a person with Tuberous Sclerosis Complex and to determine the safe dose of RAD001 without toxicity. The hypothesis is that the drug will inhibit the growth of the angiomyolipomas and possibly even cause ...
What is the current status of trial NCT00457964?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2005-08. Estimated completion is 2013-07.
What interventions are being tested in trial NCT00457964?
The interventions under investigation include: RAD001 (DRUG).
Who is sponsoring clinical trial NCT00457964?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00457964's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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