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NCT00457392 · ClinicalTrials.gov registry record · Phase 3
A Study In Patients With Non-Small Cell Lung Cancer To Test If Erlotinib Plus SU011248 Is Better Than Erlotinib Alone
A Phase 3 study of Carcinoma, Non-Small Cell Lung, sponsored by Pfizer.
- Completed
- Registry status
- Phase 3
- Development phase
- 960
- Enrollment target
- 20
- Study locations
NCT00457392: Completed Phase 3 study of Carcinoma, Non-Small Cell Lung, sponsored by Pfizer.
NCT00457392 is a Phase 3 study of Carcinoma, Non-Small Cell Lung that has completed, run by Pfizer. The registered enrollment target is 960 participants, above the 316-participant average among 130 other Carcinoma, Non-Small Cell Lung trials with a reported enrollment target (204% higher). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00457392, a Phase 3 study of Carcinoma, Non-Small Cell Lung, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 960 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study will test whether treatment with erlotinib plus SU011248 is better than erlotinib alone in patients with advanced/metastatic lung cancer who have received previous treatment with a platinum-based regimen.
Primary Outcome
Overall survival is the duration from assignment to study medication to death. For participants who are alive, overall survival is censored at the last contact.
Conditions Studied
Interventions
- DRUG placebo
- DRUG sunitinib
- DRUG erlotinib
Study Locations (20)
California
- Pfizer Investigational Site - Antioch
- Pfizer Investigational Site - Burbank
- Pfizer Investigational Site - Downey
- Pfizer Investigational Site - Fresno
- Pfizer Investigational Site - La Jolla
- Pfizer Investigational Site - La Jolla
- Pfizer Investigational Site - Montebello
- Pfizer Investigational Site - Pleasant Hill
- Pfizer Investigational Site - San Diego
- Pfizer Investigational Site - San Leandro
- Pfizer Investigational Site - Whittier
Florida
- Pfizer Investigational Site - Brooksville
- Pfizer Investigational Site - Cocoa Beach
- Pfizer Investigational Site - Fort Lauderdale
- Pfizer Investigational Site - Merritt Island
Alabama
- Pfizer Investigational Site - Florence
- Pfizer Investigational Site - Muscle Shoals
Arizona
- Pfizer Investigational Site - Scottsdale
Arkansas
- Pfizer Investigational Site - Hot Springs
Connecticut
- Pfizer Investigational Site - Fairfield
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 960 participants |
| Start Date | 2007-07 |
| Est. Completion | 2012-12 |
| Phase | Phase 3 |
What the finished NCT00457392 record still lists
NCT00457392 is an interventional study that assigns participants to a tested intervention. The registered 960 participants enrollment target is mid-sized for trials with a published cap, above the 316-participant average among 130 other Carcinoma, Non-Small Cell Lung trials with a reported enrollment target (204% higher).
The record links to 1 condition, with Carcinoma, Non-Small Cell Lung appearing as the primary indexed condition, and to 3 interventions - of which placebo is the first listed.
NCT00457392 names 20 study sites across 6 states, led by California, Florida, Alabama.
Frequently Asked Questions
What is clinical trial NCT00457392 about?
NCT00457392 is a clinical study titled "A Study In Patients With Non-Small Cell Lung Cancer To Test If Erlotinib Plus SU011248 Is Better Than Erlotinib Alone". This study will test whether treatment with erlotinib plus SU011248 is better than erlotinib alone in patients with advanced/metastatic lung cancer who have received previous treatment with a platinum-based regimen.
What is the current status of trial NCT00457392?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 960 participants. The study started on 2007-07. Estimated completion is 2012-12.
What conditions does trial NCT00457392 study?
This clinical trial studies the following conditions: Carcinoma, Non-Small Cell Lung.
What interventions are being tested in trial NCT00457392?
The interventions under investigation include: placebo (DRUG), sunitinib (DRUG), erlotinib (DRUG).
Who is sponsoring clinical trial NCT00457392?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00457392 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00457392's enrollment target sits among peer trials
960 8th of 130 higher than 123 of 130 other Carcinoma, Non-Small Cell Lung trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Carcinoma, Non-Small Cell Lung trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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