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NCT00425607 · ClinicalTrials.gov registry record · Phase 2

Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria

A Phase 2 study of Progeria and Hutchinson-Gilford Syndrome, sponsored by Monica E. Kleinman.

Completed
Registry status
Phase 2
Development phase
29
Enrollment target
1
Study location

NCT00425607 is a Phase 2 study of Progeria and Hutchinson-Gilford Syndrome that has completed, run by Monica E. Kleinman. The registered enrollment target is 29 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT00425607, a Phase 2 study of Progeria and Hutchinson-Gilford Syndrome, has completed, sponsored by Monica E. Kleinman.

COMPLETED
Registry status
Phase 2
Development phase
29 participants
Enrollment target
1
Study location

Study Summary

This is an open label dose adjusted phase II trial of the oral farnesyltransferase inhibitor (FTI) lonafarnib (SCH66336) for patients with HGPS and progeroid laminopathies.

Interventions

  • DRUG Lonafarnib

Study Locations (1)

Massachusetts

  • Children's Hospital Boston - Boston

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2007-05
Est. Completion 2009-10
Phase Phase 2

Sponsor

Monica E. Kleinman

1 total trials

What the Registry Record Tells You About NCT00425607

The ClinicalTrials.gov registry entry for NCT00425607 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Monica E. Kleinman, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Progeria appearing as the primary indexed condition, and to 1 intervention - of which Lonafarnib is the first listed.

NCT00425607 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00425607 about?

NCT00425607 is a clinical study titled "Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria". This is an open label dose adjusted phase II trial of the oral farnesyltransferase inhibitor (FTI) lonafarnib (SCH66336) for patients with HGPS and progeroid laminopathies.

What is the current status of trial NCT00425607?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2007-05. Estimated completion is 2009-10.

What conditions does trial NCT00425607 study?

This clinical trial studies the following conditions: Progeria, Hutchinson-Gilford Syndrome.

What interventions are being tested in trial NCT00425607?

The interventions under investigation include: Lonafarnib (DRUG).

Who is sponsoring clinical trial NCT00425607?

This trial is sponsored by Monica E. Kleinman, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00425607 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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