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NCT00423917 · ClinicalTrials.gov registry record · Phase 2

Fulvestrant and Bevacizumab in Treating Patients With Metastatic Breast Cancer

A Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 2
Development phase
36
Enrollment target

NCT00423917 is a Phase 2 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 36 participants.

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The verdict

NCT00423917, a Phase 2 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 2
Development phase
36 participants
Enrollment target

Study Summary

RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using fulvestrant may fight breast cancer by blocking the use of estrogen by the tumor cells. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Fulvestrant and bevacizumab may also stop the growth of breast cancer by blocking blood flow to the tumor. Giving fulvestrant together with bevacizumab may be an effective treatment for metastatic breast cancer. PURPOSE: This phase II trial is studying how well giving fulvestrant together with bevacizumab works in treating patients with metastatic breast cancer.

Interventions

  • DRUG fulvestrant
  • BIOLOGICAL bevacizumab

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2007-08
Est. Completion 2017-01-15
Phase Phase 2

What the Registry Record Tells You About NCT00423917

The ClinicalTrials.gov registry entry for NCT00423917 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alliance for Clinical Trials in Oncology, which has 446 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which fulvestrant is the first listed.

NCT00423917 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00423917 about?

NCT00423917 is a clinical study titled "Fulvestrant and Bevacizumab in Treating Patients With Metastatic Breast Cancer". RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using fulvestrant may fight breast cancer by blocking the use of estrogen by the tumor cells. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells t...

What is the current status of trial NCT00423917?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2007-08. Estimated completion is 2017-01-15.

What interventions are being tested in trial NCT00423917?

The interventions under investigation include: fulvestrant (DRUG), bevacizumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00423917?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.