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NCT00420524 · ClinicalTrials.gov registry record · Phase 1
A Study of Patupilone in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Function
A Phase 1 study, sponsored by Novartis Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT00420524: Completed Phase 1 study, sponsored by Novartis Pharmaceuticals.
NCT00420524 is a Phase 1 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00420524, a Phase 1 study, has completed, sponsored by Novartis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
This phase I study will determine the pharmacokinetic profile of patupilone in patients with mild or moderately impaired hepatic function within 2 cycles of treatment. The study population for this trial consists of patients with a documented advanced solid tumor. Patients will be stratified into 3 groups: those with normal liver function, and those with mild or moderate liver dysfunction.
Interventions
- DRUG Patupilone/EPO906
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2006-01 |
| Phase | Phase 1 |
What the finished NCT00420524 record still lists
NCT00420524 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 1 intervention - of which Patupilone/EPO906 is the first listed.
NCT00420524 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00420524 about?
NCT00420524 is a clinical study titled "A Study of Patupilone in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Function". This phase I study will determine the pharmacokinetic profile of patupilone in patients with mild or moderately impaired hepatic function within 2 cycles of treatment. The study population for this trial consists of patients with a documented advanced solid tumor. Patients will be stratified into 3 ...
What is the current status of trial NCT00420524?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2006-01.
What interventions are being tested in trial NCT00420524?
The interventions under investigation include: Patupilone/EPO906 (DRUG).
Who is sponsoring clinical trial NCT00420524?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00420524's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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