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NCT00404001 · ClinicalTrials.gov registry record · Phase 2
Study of Oral MD-0727 Administered to Patients With Primary Hypercholesterolemia
A Phase 2 study of Hypercholesterolemia, sponsored by Ironwood Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 150
- Enrollment target
- 20
- Study locations
NCT00404001: Completed Phase 2 study of Hypercholesterolemia, sponsored by Ironwood Pharmaceuticals.
NCT00404001 is a Phase 2 study of Hypercholesterolemia that has completed, run by Ironwood Pharmaceuticals. The registered enrollment target is 150 participants, below the 814-participant average among 62 other Hypercholesterolemia trials with a reported enrollment target (82% lower). The trial reports 20 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00404001, a Phase 2 study of Hypercholesterolemia, has completed, sponsored by Ironwood Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 150 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary objectives of this study are to evaluate the safety of MD-0727 in patients with primary hypercholesterolemia and to determine the low density lipoprotein cholesterol (LDL-C) lowering effect and dose-response of MD-0727 in patients with primary hypercholesterolemia.
Conditions Studied
Interventions
- DRUG MD-0727
Study Locations (20)
California
- Microbia Investigational Site - Los Angeles
- Microbia Investigational Site - Walnut Creek
North Carolina
- Microbia Investigational Site - Statesville
- Microbia Investigational Site - Winston-Salem
Ohio
- Microbia Investigational Site - Cincinnati
- Microbia Investigational Site - Marion
Washington
- Microbia Investigational Site - Lakewood
- Microbia Investigational Site - Olympia
Alabama
- Microbia Investigational Site - Birmingham
Florida
- Microbia Investigational Site - New Port Richey
Illinois
- Microbia Investigational Site - Chicago
Indiana
- Microbia Investigational Site - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2006-11 |
| Est. Completion | 2007-07 |
| Phase | Phase 2 |
What the finished NCT00404001 record still lists
NCT00404001 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 814-participant average among 62 other Hypercholesterolemia trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Hypercholesterolemia appearing as the primary indexed condition, and to 1 intervention - of which MD-0727 is the first listed.
NCT00404001 names 20 study sites across 16 states, led by California, North Carolina, Ohio.
Frequently Asked Questions
What is clinical trial NCT00404001 about?
NCT00404001 is a clinical study titled "Study of Oral MD-0727 Administered to Patients With Primary Hypercholesterolemia". The primary objectives of this study are to evaluate the safety of MD-0727 in patients with primary hypercholesterolemia and to determine the low density lipoprotein cholesterol (LDL-C) lowering effect and dose-response of MD-0727 in patients with primary hypercholesterolemia.
What is the current status of trial NCT00404001?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2006-11. Estimated completion is 2007-07.
What conditions does trial NCT00404001 study?
This clinical trial studies the following conditions: Hypercholesterolemia.
What interventions are being tested in trial NCT00404001?
The interventions under investigation include: MD-0727 (DRUG).
Who is sponsoring clinical trial NCT00404001?
This trial is sponsored by Ironwood Pharmaceuticals, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00404001 being conducted?
This trial has 20 study locations across Alabama, California, Florida, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypercholesterolemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00404001's enrollment target sits among peer trials
150 31st of 62 higher than 32 of 62 other Hypercholesterolemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypercholesterolemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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