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COMPLETED Phase 2

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C

NCT03051100 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine if triplet therapy with bempedoic acid (ETC-1002) 180mg, ezetimibe 10mg, and atorvastatin 20mg is effective and safe versus placebo in patients with elevated LDL cholesterol.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Atorvastatin 20mg
  • DRUG Bempedoic acid 180mg
  • DRUG Ezetimibe 10mg

Study Locations (11)

North Carolina

  • PMG Research of Cary — Cary
  • PMG Research of Charlotte — Charlotte
  • Sensenbrenner Primary Care — Charlotte
  • PMG Research of Hickory — Hickory
  • PMG Research of Raleigh — Raleigh
  • PMG Research of Rocky Mount — Rocky Mount
  • PMG Research Salisbury — Salisbury
  • PMG Research of Wilmington — Wilmington

Illinois

  • PMG Research of Christie Clinic — Champaign

South Carolina

  • PMG Research of Charleston — Mt. Pleasant

Virginia

  • Hampton Roads Center for Clinical Research — Virginia Beach

Trial Details

FieldValue
Enrollment Target 63 participants
Start Date 2017-01-19
Est. Completion 2017-07-05
Phase Phase 2

Sponsor

Esperion Therapeutics

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03051100

The ClinicalTrials.gov registry entry for NCT03051100 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 63 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Esperion Therapeutics, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hypercholesterolemia appearing as the primary indexed condition, and to 4 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03051100 reports 11 study locations spanning 4 distinct geographic areas — top geographies include North Carolina, Illinois, South Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03051100 about?

NCT03051100 is a clinical study titled "Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C". The purpose of this study is to determine if triplet therapy with bempedoic acid (ETC-1002) 180mg, ezetimibe 10mg, and atorvastatin 20mg is effective and safe versus placebo in patients with elevated LDL cholesterol.

What is the current status of trial NCT03051100?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 63 participants. The study started on 2017-01-19. Estimated completion is 2017-07-05.

What conditions does trial NCT03051100 study?

This clinical trial studies the following conditions: Hypercholesterolemia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03051100?

The interventions under investigation include: Placebo (OTHER), Atorvastatin 20mg (DRUG), Bempedoic acid 180mg (DRUG), Ezetimibe 10mg (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03051100?

This trial is sponsored by Esperion Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03051100 being conducted?

This trial has 11 study locations across Illinois, North Carolina, South Carolina, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial