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COMPLETED Phase 4

This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.

NCT00380939 · View on ClinicalTrials.gov ↗

Study Summary

This study was designed to assess the effects on coronary artery plaque using aggressive lipid-lowering therapy versus moderate lipid-lowering therapy. A substudy will examine the effect of these treatments on brachial artery vasoactivity.

Conditions Studied

Interventions

  • DRUG Atorvastatin
  • DRUG Pravastatin

Study Locations (20)

California

  • Pfizer Investigational Site — Los Angeles
  • Pfizer Investigational Site — Los Angeles
  • Pfizer Investigational Site — San Diego

Michigan

  • Pfizer Investigational Site — Kalamazoo
  • Pfizer Investigational Site — Royal Oak
  • Pfizer Investigational Site — Saint Clair

New York

  • Pfizer Investigational Site — Albany
  • Pfizer Investigational Site — New York
  • Pfizer Investigational Site — Williamsville

Florida

  • Pfizer Investigational Site — BLUE Island
  • Pfizer Investigational Site — Gainesville

Arkansas

  • Pfizer Investigational Site — Little Rock

Colorado

  • Pfizer Investigational Site — Denver

Georgia

  • Pfizer Investigational Site — Atlanta

Illinois

  • Pfizer Investigational Site — Chicago

Trial Details

FieldValue
Enrollment Target 600 participants
Start Date 1999-04
Est. Completion 2000-12
Phase Phase 4

Sponsor

Pfizer

769 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00380939

The ClinicalTrials.gov registry entry for NCT00380939 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 769 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Coronary Arteriosclerosis appearing as the primary indexed condition, and to 2 interventions — of which Atorvastatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00380939 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Michigan, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00380939 about?

NCT00380939 is a clinical study titled "This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.". This study was designed to assess the effects on coronary artery plaque using aggressive lipid-lowering therapy versus moderate lipid-lowering therapy. A substudy will examine the effect of these treatments on brachial artery vasoactivity.

What is the current status of trial NCT00380939?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 600 participants. The study started on 1999-04. Estimated completion is 2000-12.

What conditions does trial NCT00380939 study?

This clinical trial studies the following conditions: Coronary Arteriosclerosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00380939?

The interventions under investigation include: Atorvastatin (DRUG), Pravastatin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00380939?

This trial is sponsored by Pfizer, which has 769 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00380939 being conducted?

This trial has 20 study locations across Arkansas, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial