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NCT00356928 · ClinicalTrials.gov registry record · Phase 1

Cyclophosphamide Plus T-Cell Transplantation for Patients With Hematologic Malignancies

A Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Terminated
Registry status
Phase 1
Development phase
14
Enrollment target

NCT00356928 is a Phase 1 study that was terminated before completion, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 14 participants.

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The verdict

NCT00356928, a Phase 1 study, was terminated before completion, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

TERMINATED
Registry status
Phase 1
Development phase
14 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to stop the growth of abnormal blood cells, either by killing the cells or by stopping them from dividing. Giving cyclophosphamide together with donor lymphocytes that have been treated in the laboratory may be an effective treatment for myelodysplastic syndromes or myeloproliferative disorders. PURPOSE: This clinical trial is studying the best dose of donor lymphocytes when given together with cyclophosphamide in treating patients with myelodysplastic syndromes or myeloproliferative disorders.

Interventions

  • DRUG Cyclophosphamide
  • BIOLOGICAL Donor T cells

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2006-10
Est. Completion 2011-05
Phase Phase 1

What the Registry Record Tells You About NCT00356928

The ClinicalTrials.gov registry entry for NCT00356928 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Cyclophosphamide is the first listed.

NCT00356928 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00356928 about?

NCT00356928 is a clinical study titled "Cyclophosphamide Plus T-Cell Transplantation for Patients With Hematologic Malignancies". RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to stop the growth of abnormal blood cells, either by killing the cells or by stopping them from dividing. Giving cyclophosphamide together with donor lymphocytes that have been treated in the laboratory may be a...

What is the current status of trial NCT00356928?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2006-10. Estimated completion is 2011-05.

What interventions are being tested in trial NCT00356928?

The interventions under investigation include: Cyclophosphamide (DRUG), Donor T cells (BIOLOGICAL).

Who is sponsoring clinical trial NCT00356928?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.