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NCT00337168 · ClinicalTrials.gov registry record · Phase 2

S0530 Cytarabine and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

A Phase 2 study, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
36
Enrollment target

NCT00337168: Completed Phase 2 study, sponsored by SWOG Cancer Research Network.

NCT00337168 is a Phase 2 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 36 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00337168, a Phase 2 study, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
36 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as cytarabine and clofarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving cytarabine together with clofarabine works in treating patients with relapsed or refractory acute lymphoblastic leukemia.

Primary Outcome

Complete remission is defined as: less than 5% bone marrow blasts, neutrophils greater or equal to 1,000 per microliter, platelets greater than 100,000 per microliter, no blasts in the peripheral blood, and no extramedullary disease

Interventions

  • DRUG clofarabine
  • DRUG cytarabine

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2006-10
Est. Completion 2013-01
Phase Phase 2
SWOG Cancer Research Network

270 total trials

What the finished NCT00337168 record still lists

NCT00337168 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% lower).

The record links to 0 conditions, and to 2 interventions - of which clofarabine is the first listed.

NCT00337168 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00337168 about?

NCT00337168 is a clinical study titled "S0530 Cytarabine and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia". RATIONALE: Drugs used in chemotherapy, such as cytarabine and clofarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. PURPOSE: This phase I...

What is the current status of trial NCT00337168?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2006-10. Estimated completion is 2013-01.

What interventions are being tested in trial NCT00337168?

The interventions under investigation include: clofarabine (DRUG), cytarabine (DRUG).

Who is sponsoring clinical trial NCT00337168?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00337168's enrollment target sits among peer trials

36 1496th of 2000 higher than 477 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00337168, the US trial registry maintained by the National Library of Medicine. NCT00337168 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.