Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00326677 · ClinicalTrials.gov registry record · NA
Primary Prevention of Major Depression in Later Life
A NA study of Depression, sponsored by University of Maryland, College Park.
- Completed
- Registry status
- NA
- Development phase
- 306
- Enrollment target
- 2
- Study locations
NCT00326677: Completed NA study of Depression, sponsored by University of Maryland, College Park.
NCT00326677 is a NA study of Depression that has completed, run by University of Maryland, College Park. The registered enrollment target is 306 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (61% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00326677, a NA study of Depression, has completed, sponsored by University of Maryland, College Park.
- COMPLETED
- Registry status
- NA
- Development phase
- 306 participants
- Enrollment target
- 2
- Study locations
Study Summary
The Institute of Medicine has called for studies of "indicated" preventive interventions to reduce the incidence of mental illness in persons already symptomatic but not yet presenting with fully developed clinical syndromes. The investigators' Advanced Center for Interventions and Services Research in Late Life Mood Disorders has embraced the development and testing of preventive interventions as one of its key objectives. The investigators propose to test the following hypotheses related to primary prevention of major depressive episodes in old age, focusing on elderly patients who have symptoms of emotional distress but who are not yet presenting with the full syndrome of a major depressive episode. Hypothesis 1: Problem solving therapy (PST) will be superior to an attention-only control (dietary education) in lowering the two-year incidence of episodes of syndromal major depression in already symptomatic elderly primary care patients. Hypothesis 2: PST will also prevent higher levels of depressive symptoms and associated disabilities, over a two-year period of follow-up.
Conditions Studied
Interventions
- BEHAVIORAL Problem Solving Therapy
- BEHAVIORAL Dietary Education
Study Locations (2)
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 306 participants |
| Start Date | 2006-05 |
| Est. Completion | 2013-12 |
| Phase | NA |
What the finished NCT00326677 record still lists
NCT00326677 is an interventional study that assigns participants to a tested intervention. The registered 306 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (61% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Problem Solving Therapy is the first listed.
NCT00326677 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00326677 about?
NCT00326677 is a clinical study titled "Primary Prevention of Major Depression in Later Life". The Institute of Medicine has called for studies of "indicated" preventive interventions to reduce the incidence of mental illness in persons already symptomatic but not yet presenting with fully developed clinical syndromes. The investigators' Advanced Center for Interventions and Services Researc...
What is the current status of trial NCT00326677?
This trial is currently completed. It is a NA study. The enrollment target is 306 participants. The study started on 2006-05. Estimated completion is 2013-12.
What conditions does trial NCT00326677 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT00326677?
The interventions under investigation include: Problem Solving Therapy (BEHAVIORAL), Dietary Education (BEHAVIORAL).
Who is sponsoring clinical trial NCT00326677?
This trial is sponsored by University of Maryland, College Park, which has 46 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00326677 being conducted?
This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00326677's enrollment target sits among peer trials
306 137th of 679 higher than 542 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Reaching Out to Distressed Medical Residents, Fellows and Faculty
RECRUITING · NA
-
IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)
RECRUITING · NA
-
Cold and Heat Investigation to Lower Levels of Depression
RECRUITING · NA
-
Dosing rTMS for Depression Post-SCI
RECRUITING · NA
-
Exploring Virtual Reality Adventure Training Exergaming
RECRUITING · NA
-
Brief Interventions for Coping with Distress
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05078970 · 306 participants · NA
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
- NCT05843695 · 306 participants · NA
Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety
- NCT06498635 · 306 participants · Phase 3
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
- NCT06534918 · 306 participants · NA
Precise Oncology Interventions in Nutrition and Training (OnPoint)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia