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NCT00311350 · ClinicalTrials.gov registry record · Phase 1
Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects
A Phase 1 study of Constipation and Postoperative Complications, sponsored by Bausch Health Americas.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT00311350: Completed Phase 1 study of Constipation and Postoperative Complications, sponsored by Bausch Health Americas.
NCT00311350 is a Phase 1 study of Constipation and Postoperative Complications that has completed, run by Bausch Health Americas. The registered enrollment target is 48 participants, below the 205-participant average among 54 other Constipation trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00311350, a Phase 1 study of Constipation and Postoperative Complications, has completed, sponsored by Bausch Health Americas.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
This is the first multiple-dose experience in humans with MOA-728 in an oral formulation. This study will provide an assessment of the safety, tolerability, and pharmacokinetics (PK) of MOA-728 following administration of ascending multiple oral doses to healthy subjects.
Conditions Studied
Interventions
- DRUG MOA-728
Study Locations (1)
Pennsylvania
- - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2006-03 |
| Est. Completion | 2006-08 |
| Phase | Phase 1 |
What the finished NCT00311350 record still lists
NCT00311350 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 205-participant average among 54 other Constipation trials with a reported enrollment target (77% lower).
The record links to 2 conditions, with Constipation appearing as the primary indexed condition, and to 1 intervention - of which MOA-728 is the first listed.
NCT00311350 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00311350 about?
NCT00311350 is a clinical study titled "Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects". This is the first multiple-dose experience in humans with MOA-728 in an oral formulation. This study will provide an assessment of the safety, tolerability, and pharmacokinetics (PK) of MOA-728 following administration of ascending multiple oral doses to healthy subjects.
What is the current status of trial NCT00311350?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2006-03. Estimated completion is 2006-08.
What conditions does trial NCT00311350 study?
This clinical trial studies the following conditions: Constipation, Postoperative Complications.
What interventions are being tested in trial NCT00311350?
The interventions under investigation include: MOA-728 (DRUG).
Who is sponsoring clinical trial NCT00311350?
This trial is sponsored by Bausch Health Americas, which has 168 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00311350 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Constipation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00311350's enrollment target sits among peer trials
48 37th of 54 higher than 17 of 54 other Constipation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Constipation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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