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NCT00303888 · ClinicalTrials.gov registry record · Phase 1

Docetaxel With or Without Phenoxodiol in Treating Patients With Recurrent Advanced Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer

A Phase 1 study, sponsored by Yale University.

Terminated
Registry status
Phase 1
Development phase
31
Enrollment target

NCT00303888: Clinical Trial Phase 1 study, sponsored by Yale University.

NCT00303888 is a Phase 1 study that was terminated before completion, run by Yale University. The registered enrollment target is 31 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00303888, a Phase 1 study, was terminated before completion, sponsored by Yale University.

TERMINATED
Registry status
Phase 1
Development phase
31 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Phenoxodiol may help docetaxel work better by making tumor cells more sensitive to the drug. PURPOSE: This randomized phase I/II trial is studying the side effects of docetaxel when given together with either phenoxodiol or placebo and to see how well it works in treating patients with recurrent advanced ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cavity cancer.

Interventions

  • OTHER placebo
  • DRUG docetaxel
  • DRUG idronoxil

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2006-05
Est. Completion 2009-10
Phase Phase 1
Yale University

1,492 total trials

Why NCT00303888 stopped before completion

NCT00303888 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower).

The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.

NCT00303888 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00303888 about?

NCT00303888 is a clinical study titled "Docetaxel With or Without Phenoxodiol in Treating Patients With Recurrent Advanced Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer". RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Phenoxodiol may help docetaxel work better by making tumor cells more sensitive to the drug. PURPOSE: This randomized ph...

What is the current status of trial NCT00303888?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2006-05. Estimated completion is 2009-10.

What interventions are being tested in trial NCT00303888?

The interventions under investigation include: placebo (OTHER), docetaxel (DRUG), idronoxil (DRUG).

Who is sponsoring clinical trial NCT00303888?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00303888's enrollment target sits among peer trials

31 1322nd of 2000 higher than 669 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00303888, the US trial registry maintained by the National Library of Medicine. NCT00303888 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.