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NCT00282282 · ClinicalTrials.gov registry record · Phase 2
Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation
A Phase 2 study, sponsored by Dana-Farber Cancer Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 31
- Enrollment target
NCT00282282: Completed Phase 2 study, sponsored by Dana-Farber Cancer Institute.
NCT00282282 is a Phase 2 study that has completed, run by Dana-Farber Cancer Institute. The registered enrollment target is 31 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00282282, a Phase 2 study, has completed, sponsored by Dana-Farber Cancer Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 31 participants
- Enrollment target
Study Summary
The purpose of this study is to extend the use of Tacrolimus and Sirolimus to determine how effective it is in preventing graft versus host disease (GVHD)in patients that have received non-myeloablative peripheral blood stem cell transplantation.
Primary Outcome
All participants received tacrolimus and sirolimus in this one arm study. There were no participants considered unevaluable for this measure (deceased prior to day 100). The total number of people who developed grade II-IV aGVHD before day 100 are reported here.
Interventions
- DRUG fludarabine
- DRUG tacrolimus
- DRUG sirolimus
- DRUG busulfex
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2006-01 |
| Est. Completion | 2009-07 |
| Phase | Phase 2 |
What the finished NCT00282282 record still lists
NCT00282282 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 4 interventions - of which fludarabine is the first listed.
NCT00282282 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00282282 about?
NCT00282282 is a clinical study titled "Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation". The purpose of this study is to extend the use of Tacrolimus and Sirolimus to determine how effective it is in preventing graft versus host disease (GVHD)in patients that have received non-myeloablative peripheral blood stem cell transplantation.
What is the current status of trial NCT00282282?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 31 participants. The study started on 2006-01. Estimated completion is 2009-07.
What interventions are being tested in trial NCT00282282?
The interventions under investigation include: fludarabine (DRUG), tacrolimus (DRUG), sirolimus (DRUG), busulfex (DRUG).
Who is sponsoring clinical trial NCT00282282?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00282282's enrollment target sits among peer trials
31 1578th of 2000 higher than 419 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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