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COMPLETED

Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission

NCT00268528 · View on ClinicalTrials.gov ↗

Study Summary

This clinical trial is assessing compliance with long-term mercaptopurine treatment in young patients with acute lymphoblastic leukemia in remission. Assessing why young patients who have acute lymphoblastic leukemia may not take their medications as prescribed may help identify ways to assist them in taking their medications more consistently and may improve long-term treatment outcomes.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • OTHER Questionnaire Administration
  • DRUG Methotrexate
  • DRUG Mercaptopurine
  • BEHAVIORAL Compliance Monitoring

Study Locations (20)

California

  • Kaiser Permanente Downey Medical Center — Downey
  • City of Hope Comprehensive Cancer Center — Duarte
  • Loma Linda University Medical Center — Loma Linda
  • Miller Children's and Women's Hospital Long Beach — Long Beach
  • Children's Hospital Los Angeles — Los Angeles
  • Mattel Children's Hospital UCLA — Los Angeles
  • UCLA / Jonsson Comprehensive Cancer Center — Los Angeles
  • Valley Children's Hospital — Madera
  • Children's Hospital and Research Center at Oakland — Oakland
  • Lucile Packard Children's Hospital Stanford University — Palo Alto
  • University of California Davis Comprehensive Cancer Center — Sacramento
  • Rady Children's Hospital - San Diego — San Diego
  • UCSF Medical Center-Parnassus — San Francisco
  • Harbor-University of California at Los Angeles Medical Center — Torrance

Alabama

  • Children's Hospital of Alabama — Birmingham
  • University of Alabama at Birmingham Cancer Center — Birmingham

Connecticut

  • University of Connecticut — Farmington
  • Connecticut Children's Medical Center — Hartford

Arkansas

  • University of Arkansas for Medical Sciences — Little Rock

Colorado

  • Children's Hospital Colorado — Aurora

Trial Details

FieldValue
Enrollment Target 720 participants
Start Date 2005-05-30
Est. Completion 2020-06-30

Sponsor

Children's Oncology Group

318 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00268528

The ClinicalTrials.gov registry entry for NCT00268528 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 720 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Oncology Group, which has 318 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Childhood Acute Lymphoblastic Leukemia in Remission appearing as the primary indexed condition, and to 5 interventions — of which Laboratory Biomarker Analysis is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00268528 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Alabama, Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00268528 about?

NCT00268528 is a clinical study titled "Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission". This clinical trial is assessing compliance with long-term mercaptopurine treatment in young patients with acute lymphoblastic leukemia in remission. Assessing why young patients who have acute lymphoblastic leukemia may not take their medications as prescribed may help identify ways to assist them ...

What is the current status of trial NCT00268528?

This trial is currently completed. The enrollment target is 720 participants. The study started on 2005-05-30. Estimated completion is 2020-06-30.

What conditions does trial NCT00268528 study?

This clinical trial studies the following conditions: Childhood Acute Lymphoblastic Leukemia in Remission. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00268528?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Questionnaire Administration (OTHER), Methotrexate (DRUG), Mercaptopurine (DRUG), Compliance Monitoring (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00268528?

This trial is sponsored by Children's Oncology Group, which has 318 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00268528 being conducted?

This trial has 20 study locations across Alabama, Arkansas, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial