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NCT00176436 · ClinicalTrials.gov registry record · Phase 4
Atomoxetine for Treatment of Weight Gain in Olanzapine or Clozapine Patients
A Phase 4 study of Schizophrenia, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT00176436: Completed Phase 4 study of Schizophrenia, sponsored by University of Maryland, Baltimore.
NCT00176436 is a Phase 4 study of Schizophrenia that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 40 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00176436, a Phase 4 study of Schizophrenia, has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The study investigates the use of Atomoxetine in combination with exercise and a diet support group (Weight Watchers)to treat weight gain associated with Olanzapine or clozapine. All patients must be adults who have been diagnosed with Schizophrenia or Schizoaffective Disorder.
Primary Outcome
Weight loss was measured each week over the 24 week study period. Intent to treat analyses of treatment effects on the primary outcome (weight) were conducted using all observed weight measurements from all participants with post-baseline weight measurements, using the mixed model for unbalanced repeated measures ANOVA. This model summarizes change in weight for each participant by the average change in weight per week (slope) over 24 weeks, and compares these slopes between the two groups.
Conditions Studied
Interventions
- BEHAVIORAL Diet support group
- BEHAVIORAL Group counseling and exercise
Study Locations (1)
Maryland
- Maryland Psychiatric Research Center - Catonsville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2004-02 |
| Est. Completion | 2008-03 |
| Phase | Phase 4 |
What the finished NCT00176436 record still lists
NCT00176436 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Diet support group is the first listed.
NCT00176436 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00176436 about?
NCT00176436 is a clinical study titled "Atomoxetine for Treatment of Weight Gain in Olanzapine or Clozapine Patients". The study investigates the use of Atomoxetine in combination with exercise and a diet support group (Weight Watchers)to treat weight gain associated with Olanzapine or clozapine. All patients must be adults who have been diagnosed with Schizophrenia or Schizoaffective Disorder.
What is the current status of trial NCT00176436?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2004-02. Estimated completion is 2008-03.
What conditions does trial NCT00176436 study?
This clinical trial studies the following conditions: Schizophrenia.
What interventions are being tested in trial NCT00176436?
The interventions under investigation include: Diet support group (BEHAVIORAL), Group counseling and exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT00176436?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00176436 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00176436's enrollment target sits among peer trials
40 233rd of 315 higher than 73 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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