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NCT00144963 · ClinicalTrials.gov registry record · Phase 1
Liposomal Vincristine Plus Dexamethasone in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
A Phase 1 study, sponsored by Acrotech Biopharma.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT00144963: Completed Phase 1 study, sponsored by Acrotech Biopharma.
NCT00144963 is a Phase 1 study that has completed, run by Acrotech Biopharma. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00144963, a Phase 1 study, has completed, sponsored by Acrotech Biopharma.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
The purpose of this study is to find the highest safe dose and to assess the anti-tumor effect of liposomal vincristine with dexamethasone in patients with relapsed or refractory acute lymphoblastic leukemia (ALL).
Primary Outcome
Subjects had to receive at least 1 course consisting of 4 weekly infusions of VSLI at the assigned drug dose with a minimum 2 weeks of observation after the last VSLI dose to be included in the evaluation of the MTD.
Interventions
- DRUG Dexamethasone
- DRUG Vincristine Sulfate Liposomes Injection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2002-07 |
| Est. Completion | 2006-08 |
| Phase | Phase 1 |
What the finished NCT00144963 record still lists
NCT00144963 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 2 interventions - of which Dexamethasone is the first listed.
NCT00144963 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00144963 about?
NCT00144963 is a clinical study titled "Liposomal Vincristine Plus Dexamethasone in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia". The purpose of this study is to find the highest safe dose and to assess the anti-tumor effect of liposomal vincristine with dexamethasone in patients with relapsed or refractory acute lymphoblastic leukemia (ALL).
What is the current status of trial NCT00144963?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2002-07. Estimated completion is 2006-08.
What interventions are being tested in trial NCT00144963?
The interventions under investigation include: Dexamethasone (DRUG), Vincristine Sulfate Liposomes Injection (DRUG).
Who is sponsoring clinical trial NCT00144963?
This trial is sponsored by Acrotech Biopharma, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00144963's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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