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NCT00121511 · ClinicalTrials.gov registry record · NA
The Effect of Efudex Treatment on Photoaged Skin
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
NCT00121511 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 21 participants.
The verdict
NCT00121511, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
Study Summary
The researchers propose that skin improvements may be seen following a course of Efudex, (5-fluorouracil), a FDA-approved topical therapy (applied directly to the skin). These improvements could be the result of both a reduction of actinic keratoses (small red horny growths or flesh-colored wartlike growths caused by overexposure to ultraviolet radiation or the sun) and improvement of sun-damaged skin. In addition, this research study is being done to determine if the expression of p53, a tumor suppressor gene (its activity stops the formation of tumors), is decreased following Efudex treatment. Mutations (abnormal changes) in the gene, called p53, are associated with a certain type of skin cancer. In addition, p53-mutated genes are known to exist in non-cancerous sun-damaged skin. Thus, the presence of p53 mutations may serve as a marker for both sun damage and an elevated risk of developing skin cancer.
Interventions
- DRUG Efudex (5-fluorouracil)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2005-07 |
| Est. Completion | 2007-07 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00121511
The ClinicalTrials.gov registry entry for NCT00121511 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Efudex (5-fluorouracil) is the first listed.
NCT00121511 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00121511 about?
NCT00121511 is a clinical study titled "The Effect of Efudex Treatment on Photoaged Skin". The researchers propose that skin improvements may be seen following a course of Efudex, (5-fluorouracil), a FDA-approved topical therapy (applied directly to the skin). These improvements could be the result of both a reduction of actinic keratoses (small red horny growths or flesh-colored wartlike...
What is the current status of trial NCT00121511?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2005-07. Estimated completion is 2007-07.
What interventions are being tested in trial NCT00121511?
The interventions under investigation include: Efudex (5-fluorouracil) (DRUG).
Who is sponsoring clinical trial NCT00121511?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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