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NCT00114452 · ClinicalTrials.gov registry record · Phase 1

Safety Study of Adult Mesenchymal Stem Cells (MSC) to Treat Acute Myocardial Infarction

A Phase 1 study of Myocardial Infarction, sponsored by Mesoblast.

Completed
Registry status
Phase 1
Development phase
60
Enrollment target
15
Study locations

NCT00114452 is a Phase 1 study of Myocardial Infarction that has completed, run by Mesoblast. The registered enrollment target is 60 participants, below the 4,681-participant average among 64 other Myocardial Infarction trials with a reported enrollment target (99% lower). The trial reports 15 study locations across 12 states.

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The verdict

NCT00114452, a Phase 1 study of Myocardial Infarction, has completed, sponsored by Mesoblast.

COMPLETED
Registry status
Phase 1
Development phase
60 participants
Enrollment target
15
Study locations

Study Summary

The purpose of the study is to determine whether adult stem cells \[Provacel™(PUMP1)\] are safe and possibly effective in the treatment of acute myocardial infarction (heart attack).

Conditions Studied

Myocardial Infarction

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Provacel

Study Locations (15)

Maryland

  • Johns Hopkins University - Baltimore
  • Washington Adventist - Takoma Park

New York

  • Columbia Presbyterian Hospital - New York
  • University of Rochester - Strong Memorial - Rochester

Texas

  • Austin Heart Institute - Austin
  • Texas Medical School - Houston

Arizona

  • Arizona Heart Institute - Phoenix

California

  • University of California - San Diego; Thornton - San Diego

District of Columbia

  • Washington Hospital Center - Washington D.C.

Illinois

  • Rush University Medical Center - Chicago

Indiana

  • The Care Group - Indianapolis

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2005-03-22
Est. Completion 2008-04-24
Phase Phase 1

Sponsor

Mesoblast

25 total trials

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What the Registry Record Tells You About NCT00114452

The ClinicalTrials.gov registry entry for NCT00114452 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,681-participant average among 64 other Myocardial Infarction trials with a reported enrollment target (99% lower). The listed sponsor is Mesoblast, which has 25 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Myocardial Infarction appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00114452 reports 15 study locations spanning 12 distinct geographic areas - top geographies include Maryland, New York, Texas.

Frequently Asked Questions

What is clinical trial NCT00114452 about?

NCT00114452 is a clinical study titled "Safety Study of Adult Mesenchymal Stem Cells (MSC) to Treat Acute Myocardial Infarction". The purpose of the study is to determine whether adult stem cells \[Provacel™(PUMP1)\] are safe and possibly effective in the treatment of acute myocardial infarction (heart attack).

What is the current status of trial NCT00114452?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2005-03-22. Estimated completion is 2008-04-24.

What conditions does trial NCT00114452 study?

This clinical trial studies the following conditions: Myocardial Infarction.

What interventions are being tested in trial NCT00114452?

The interventions under investigation include: Placebo (BIOLOGICAL), Provacel (BIOLOGICAL).

Who is sponsoring clinical trial NCT00114452?

This trial is sponsored by Mesoblast, which has 25 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00114452 being conducted?

This trial has 15 study locations across Arizona, California, District of Columbia, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.