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NCT00108173 · ClinicalTrials.gov registry record · Phase 1
Brain Reaction to Treatment of Nicotine Dependence
A Phase 1 study of Nicotine Dependence, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- Phase 1
- Development phase
- 104
- Enrollment target
- 1
- Study location
NCT00108173: Completed Phase 1 study of Nicotine Dependence, sponsored by US Department of Veterans Affairs.
NCT00108173 is a Phase 1 study of Nicotine Dependence that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 104 participants, below the 185-participant average among 67 other Nicotine Dependence trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00108173, a Phase 1 study of Nicotine Dependence, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 104 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study was to determine how the treatments for cigarette craving work. Hypothesis: During exposure to cigarette-related cues, heavy smokers will have greater reductions in regional brain activation from before to after both forms of active treatments than from before to after placebo.
Primary Outcome
Brain activity and activation in response to cigarette-related cues
Conditions Studied
Interventions
- DRUG Zyban
Study Locations (1)
California
- VA Greater Los Angeles Healthcare System, West LA - West Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104 participants |
| Start Date | 2002-10 |
| Est. Completion | 2011-06 |
| Phase | Phase 1 |
What the finished NCT00108173 record still lists
NCT00108173 is an interventional study that assigns participants to a tested intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap, below the 185-participant average among 67 other Nicotine Dependence trials with a reported enrollment target (44% lower).
The record links to 1 condition, with Nicotine Dependence appearing as the primary indexed condition, and to 1 intervention - of which Zyban is the first listed.
NCT00108173 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00108173 about?
NCT00108173 is a clinical study titled "Brain Reaction to Treatment of Nicotine Dependence". The purpose of the study was to determine how the treatments for cigarette craving work. Hypothesis: During exposure to cigarette-related cues, heavy smokers will have greater reductions in regional brain activation from before to after both forms of active treatments than from before to after plac...
What is the current status of trial NCT00108173?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 104 participants. The study started on 2002-10. Estimated completion is 2011-06.
What conditions does trial NCT00108173 study?
This clinical trial studies the following conditions: Nicotine Dependence.
What interventions are being tested in trial NCT00108173?
The interventions under investigation include: Zyban (DRUG).
Who is sponsoring clinical trial NCT00108173?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00108173 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Nicotine Dependence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00108173's enrollment target sits among peer trials
104 34th of 67 higher than 34 of 67 other Nicotine Dependence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Nicotine Dependence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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