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NCT00069823 · ClinicalTrials.gov registry record · Phase 3
Study of Acid Reflux in Asthma
A Phase 3 study of Asthma and Lung Diseases, sponsored by Johns Hopkins Bloomberg School of Public Health.
- Completed
- Registry status
- Phase 3
- Development phase
- 403
- Enrollment target
- 20
- Study locations
NCT00069823: Completed Phase 3 study of Asthma and Lung Diseases, sponsored by Johns Hopkins Bloomberg School of Public Health.
NCT00069823 is a Phase 3 study of Asthma and Lung Diseases that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 403 participants, below the 1,562-participant average among 374 other Asthma trials with a reported enrollment target (74% lower). The trial reports 20 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00069823, a Phase 3 study of Asthma and Lung Diseases, has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 403 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to determine if subjects with symptomatic asthma who are assigned to treatment with a proton pump inhibitor (PPI) drug such as Nexium have fewer asthma attacks than similar subjects assigned to placebo treatment.
Primary Outcome
Episodes of poor asthma control was defined as any one of the following: 2 consecutive days with a drop in peak flow \>=30% of baseline; urgent care for asthma; or new use of oral corticosteroids for asthma
Conditions Studied
Interventions
- DRUG Esomeprazole
- DRUG Placebo proton pump inhibitor
Study Locations (20)
New York
- North Shore-LIJ Medical Center - New Hyde Park
- NYU School of Medicine - New York
- New York Medical College - Valhalla
Florida
- Nemours Childrens Clinic - Jacksonville
- University of Miami - Miami
Missouri
- Univ of MO Kansas City School of Medicine - Kansas City
- Washington University School of Medicine - St Louis
Alabama
- University of Alabama at Birmingham - Birmingham
California
- University of California, San Diego - San Diego
Colorado
- National Jewish Medical and Research Center - Denver
Georgia
- Emory University - Atlanta
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 403 participants |
| Start Date | 2003-09 |
| Est. Completion | 2008-05 |
| Phase | Phase 3 |
What the finished NCT00069823 record still lists
NCT00069823 is an interventional study that assigns participants to a tested intervention. The registered 403 participants enrollment target is mid-sized for trials with a published cap, below the 1,562-participant average among 374 other Asthma trials with a reported enrollment target (74% lower).
The record links to 3 conditions, with Asthma appearing as the primary indexed condition, and to 2 interventions - of which Esomeprazole is the first listed.
NCT00069823 names 20 study sites across 16 states, led by New York, Florida, Missouri.
Frequently Asked Questions
What is clinical trial NCT00069823 about?
NCT00069823 is a clinical study titled "Study of Acid Reflux in Asthma". The purpose of this study is to determine if subjects with symptomatic asthma who are assigned to treatment with a proton pump inhibitor (PPI) drug such as Nexium have fewer asthma attacks than similar subjects assigned to placebo treatment.
What is the current status of trial NCT00069823?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 403 participants. The study started on 2003-09. Estimated completion is 2008-05.
What conditions does trial NCT00069823 study?
This clinical trial studies the following conditions: Asthma, Lung Diseases, Lung Diseases, Obstructive.
What interventions are being tested in trial NCT00069823?
The interventions under investigation include: Esomeprazole (DRUG), Placebo proton pump inhibitor (DRUG).
Who is sponsoring clinical trial NCT00069823?
This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00069823 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Asthma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00069823's enrollment target sits among peer trials
403 92nd of 374 higher than 283 of 374 other Asthma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Asthma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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