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NCT00066911 · ClinicalTrials.gov registry record
Brain Mapping of Voice Control
A clinical trial of Voice Disorders, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 174
- Enrollment target
- 1
- Study location
NCT00066911: Completed study of Voice Disorders, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00066911 is a study of Voice Disorders that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 174 participants, above the 72-participant average among 7 other Voice Disorders trials with a reported enrollment target (142% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00066911, a study of Voice Disorders, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 174 participants
- Enrollment target
- 1
- Study location
Study Summary
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the voice box affect brain control of the voice box; 3) how the central nervous system is affected when people have motor or sensory abnormalities that affect the voice box; and 4) whether patients with voice disorders differ from people without voice disorders in the way the brain controls the voice box. By better understanding these concepts, researchers hope to develop improved treatments for patients with voice disorders. Forty-five healthy adult volunteers and 90 patients with voice disorders will participate in this study. Participants must be between the ages of 20 and 70. The study will involve two visits to the Clinical Center. During the first visit, participants will undergo a medical history and physical exam. During the second visit, investigators will perform the following procedures on study participants: 1) look at the voice box with a nasolaryngoscope, a fine tube through the nose; 2) use MRI \[magnetic resonance imaging\] to record brain activity while participants use their voice to speak; 3) changing sensation in the voice box by dripping a topical anesthetic onto the vocal folds; and 4) using MRI to again record brain activity during speech immediately after applying the topical anesthetic. Participants will receive up to $700 in compensation for their involvement in this study.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 174 participants |
| Start Date | 2003-08-02 |
What the finished NCT00066911 record still lists
NCT00066911 is an observational study that tracks outcomes without assigning an intervention. The registered 174 participants enrollment target is mid-sized for trials with a published cap, above the 72-participant average among 7 other Voice Disorders trials with a reported enrollment target (142% higher).
The record links to 1 condition, with Voice Disorders appearing as the primary indexed condition, and to 0 interventions.
NCT00066911 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00066911 about?
NCT00066911 is a clinical study titled "Brain Mapping of Voice Control". Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the voice box affect brain control of the voice box; 3) how the central nervo...
What is the current status of trial NCT00066911?
This trial is currently completed. The enrollment target is 174 participants. The study started on 2003-08-02.
What conditions does trial NCT00066911 study?
This clinical trial studies the following conditions: Voice Disorders.
Who is sponsoring clinical trial NCT00066911?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00066911 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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