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NCT00065988 · ClinicalTrials.gov registry record · Phase 3
The Children's Amalgam Trial
A Phase 3 study of Dental Caries, sponsored by Carelon Research.
- Completed
- Registry status
- Phase 3
- Development phase
- 534
- Enrollment target
- 1
- Study location
NCT00065988: Completed Phase 3 study of Dental Caries, sponsored by Carelon Research.
NCT00065988 is a Phase 3 study of Dental Caries that has completed, run by Carelon Research. The registered enrollment target is 534 participants, below the 704-participant average among 30 other Dental Caries trials with a reported enrollment target (24% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00065988, a Phase 3 study of Dental Caries, has completed, sponsored by Carelon Research.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 534 participants
- Enrollment target
- 1
- Study location
Study Summary
The Children's Amalgam Trial is one of only two randomized trials of its kind, and the only such trial in the United States, to address the potential impact of mercury exposure from amalgam restorations on neuropsychological and renal function in children.
Conditions Studied
Interventions
- DEVICE Dispersed phase amalgam restoration /composite restoration
Study Locations (1)
Massachusetts
- New England Research Institute - Watertown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 534 participants |
| Start Date | 1997-09 |
| Est. Completion | 2005-03 |
| Phase | Phase 3 |
What the finished NCT00065988 record still lists
NCT00065988 is an interventional study that assigns participants to a tested intervention. The registered 534 participants enrollment target is mid-sized for trials with a published cap, below the 704-participant average among 30 other Dental Caries trials with a reported enrollment target (24% lower).
The record links to 1 condition, with Dental Caries appearing as the primary indexed condition, and to 1 intervention - of which Dispersed phase amalgam restoration /composite restoration is the first listed.
NCT00065988 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00065988 about?
NCT00065988 is a clinical study titled "The Children's Amalgam Trial". The Children's Amalgam Trial is one of only two randomized trials of its kind, and the only such trial in the United States, to address the potential impact of mercury exposure from amalgam restorations on neuropsychological and renal function in children.
What is the current status of trial NCT00065988?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 534 participants. The study started on 1997-09. Estimated completion is 2005-03.
What conditions does trial NCT00065988 study?
This clinical trial studies the following conditions: Dental Caries.
What interventions are being tested in trial NCT00065988?
The interventions under investigation include: Dispersed phase amalgam restoration /composite restoration (DEVICE).
Who is sponsoring clinical trial NCT00065988?
This trial is sponsored by Carelon Research, which has 50 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00065988 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dental Caries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00065988's enrollment target sits among peer trials
534 7th of 30 higher than 24 of 30 other Dental Caries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dental Caries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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