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NCT06921603 · ClinicalTrials.gov registry record · NA
POCUS-Guided Diuresis for Decompensated Heart Failure
A NA study of Heart Decompensation, Acute and Acute Kidney Injuries, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 588
- Enrollment target
- 5
- Study locations
NCT06921603 is a NA study of Heart Decompensation, Acute and Acute Kidney Injuries that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 588 participants. The trial reports 5 study locations across 1 state.
The verdict
NCT06921603, a NA study of Heart Decompensation, Acute and Acute Kidney Injuries, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 588 participants
- Enrollment target
- 5
- Study locations
Study Summary
Heart failure occurs when the heart cannot pump blood effectively, leading to fluid buildup in the body. This can cause problems such as difficulty breathing, swelling, and extreme tiredness. In severe cases, these symptoms worsen to the point where hospitalization is required. Unfortunately, many patients with severe heart failure are readmitted to the hospital within 30 days after discharge, which is both physically and emotionally challenging for patients and places a significant financial burden on individuals and the healthcare system. Although symptoms such as difficulty breathing and swelling may improve during the hospital stay, some patients are discharged with excess fluid remaining in their bodies. This retained fluid often causes symptoms to worsen, leading to subsequent hospital readmissions. Inadequate management of fluid levels can also harm the kidneys, further complicating the patient's condition. This study aims to improve care for heart failure patients by utilizing a simple, non-invasive tool to assess fluid levels more accurately at the bedside. The tool measures the size of a large blood vessel in the neck, providing key information about the pressure inside the heart. This information enables clinicians to determine the appropriate amount of medication needed to remove just the right amount of fluid. Properly managing fluid levels can help prevent kidney damage and improve overall patient outcomes. The primary goal of this study is to evaluate whether this tool can reduce the number of patients readmitted to the hospital within 30 days of discharge. A secondary goal is to determine whether the tool can help protect kidney function by allowing for better fluid management. If successful, this approach has the potential to help heart failure patients stay healthier, reduce hospital visits, and lower healthcare costs.
Conditions Studied
Interventions
- OTHER Furosemide (Standard Diuretic) Treatment
- OTHER POCUS-Assessed Diuretic Management
Study Locations (5)
Pennsylvania
- UPMC East - Pittsburgh
- University of Pittsburgh Medical Center - Pittsburgh
- UPMC Presbyterian - Pittsburgh
- UPMC Mercy - Pittsburgh
- UPMC Shadyside - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 588 participants |
| Start Date | 2025-06-29 |
| Est. Completion | 2026-12 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06921603
The ClinicalTrials.gov registry entry for NCT06921603 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 588 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Heart Decompensation, Acute appearing as the primary indexed condition, and to 2 interventions - of which Furosemide (Standard Diuretic) Treatment is the first listed.
NCT06921603 reports 5 study locations spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06921603 about?
NCT06921603 is a clinical study titled "POCUS-Guided Diuresis for Decompensated Heart Failure". Heart failure occurs when the heart cannot pump blood effectively, leading to fluid buildup in the body. This can cause problems such as difficulty breathing, swelling, and extreme tiredness. In severe cases, these symptoms worsen to the point where hospitalization is required. Unfortunately, many p...
What is the current status of trial NCT06921603?
This trial is currently recruiting. It is a NA study. The enrollment target is 588 participants. The study started on 2025-06-29. Estimated completion is 2026-12.
What conditions does trial NCT06921603 study?
This clinical trial studies the following conditions: Heart Decompensation, Acute, Acute Kidney Injuries.
What interventions are being tested in trial NCT06921603?
The interventions under investigation include: Furosemide (Standard Diuretic) Treatment (OTHER), POCUS-Assessed Diuretic Management (OTHER).
Who is sponsoring clinical trial NCT06921603?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06921603 being conducted?
This trial has 5 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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