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NCT00058695 · ClinicalTrials.gov registry record
Genetic Factors in Age-Related Macular Degeneration
A clinical trial, sponsored by National Eye Institute (NEI).
- Terminated
- Registry status
- 477
- Enrollment target
NCT00058695: Clinical Trial study, sponsored by National Eye Institute (NEI).
NCT00058695 is a clinical trial that was terminated before completion, run by National Eye Institute (NEI). The registered enrollment target is 477 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00058695 was terminated before completion, sponsored by National Eye Institute (NEI).
- TERMINATED
- Registry status
- 477 participants
- Enrollment target
Study Summary
This study will examine whether certain polymorphisms (small gene variances) predispose people to develop age-related macular degeneration (AMD). This eye condition affects people over 50 years of age and can cause permanent loss of central vision. The study will examine and compare the frequency of polymorphisms in patients with AMD to that of individuals without AMD. This information will help identify genetic risk factors for the AMD and may lead to the development of more effective treatments. Patients 50 years of age and older with advanced AMD and healthy normal volunteers may be eligible for this study. All participants will provide an eye health history and will have 10 milliliters (2 teaspoons) of blood drawn from an arm vein. The DNA in the blood will be isolated and tested for certain genes that other research indicates are important in aging and age-related diseases. The normal and polymorphic gene sequences will be identified and compared in patients with AMD and control subjects to determine if any of the polymorphisms are related to development of AMD. In addition, control subjects will have a routine eye examination, including dilation of the pupils for examination of the back of the eye. ...
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 477 participants |
| Start Date | 2003-04-04 |
| Est. Completion | 2015-10-21 |
Why NCT00058695 stopped before completion
NCT00058695 is an observational study that tracks outcomes without assigning an intervention. The registered 477 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00058695 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00058695 about?
NCT00058695 is a clinical study titled "Genetic Factors in Age-Related Macular Degeneration". This study will examine whether certain polymorphisms (small gene variances) predispose people to develop age-related macular degeneration (AMD). This eye condition affects people over 50 years of age and can cause permanent loss of central vision. The study will examine and compare the frequency of...
What is the current status of trial NCT00058695?
This trial is currently terminated. The enrollment target is 477 participants. The study started on 2003-04-04. Estimated completion is 2015-10-21.
Who is sponsoring clinical trial NCT00058695?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
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